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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V0A4
All Species:
13.64
Human Site:
T275
Identified Species:
27.27
UniProt:
Q9HBG4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBG4
NP_065683.2
840
96358
T275
E
D
L
I
T
V
I
T
Q
T
E
S
H
R
Q
Chimpanzee
Pan troglodytes
XP_511508
838
96562
N280
D
D
L
Q
M
V
L
N
Q
T
E
D
H
R
Q
Rhesus Macaque
Macaca mulatta
XP_001105743
987
112668
T424
E
D
L
I
T
V
I
T
Q
T
E
S
H
R
Q
Dog
Lupus familis
XP_539895
839
96055
T275
E
D
L
I
T
V
I
T
Q
T
E
S
H
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q920R6
833
95587
T275
E
D
L
I
T
V
I
T
Q
T
E
S
H
R
Q
Rat
Rattus norvegicus
P25286
838
96309
N273
D
D
L
Q
M
V
L
N
Q
T
E
D
H
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9I8D0
838
95966
N273
D
D
L
Q
M
V
L
N
Q
T
E
D
H
R
Q
Frog
Xenopus laevis
Q8AVM5
831
95538
N273
E
D
L
Q
M
V
L
N
Q
T
E
D
H
R
Q
Zebra Danio
Brachydanio rerio
NP_001018502
839
95617
N273
D
D
L
Q
M
V
L
N
Q
T
E
D
H
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P30628
905
103383
G309
E
D
L
K
T
V
L
G
Q
T
Q
D
H
R
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32563
840
95510
K289
S
D
L
Y
T
V
L
K
T
T
S
T
T
L
E
Red Bread Mold
Neurospora crassa
Q01290
856
97974
R294
E
D
V
Q
N
V
L
R
N
T
Q
Q
T
L
E
Conservation
Percent
Protein Identity:
100
61.9
83.5
90.9
N.A.
85.8
62.2
N.A.
N.A.
61.3
61.4
60.5
N.A.
N.A.
N.A.
51.1
N.A.
Protein Similarity:
100
77.3
84.3
95.4
N.A.
91.9
76.9
N.A.
N.A.
76.6
77
76.3
N.A.
N.A.
N.A.
66.9
N.A.
P-Site Identity:
100
60
100
100
N.A.
100
60
N.A.
N.A.
60
66.6
60
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
100
73.3
100
100
N.A.
100
73.3
N.A.
N.A.
73.3
73.3
73.3
N.A.
N.A.
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
39.5
41.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
59.4
60.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
100
0
0
0
0
0
0
0
0
0
50
0
0
0
% D
% Glu:
59
0
0
0
0
0
0
0
0
0
75
0
0
0
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
84
0
9
% H
% Ile:
0
0
0
34
0
0
34
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
92
0
0
0
67
0
0
0
0
0
0
17
0
% L
% Met:
0
0
0
0
42
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
42
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
50
0
0
0
0
84
0
17
9
0
0
75
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
0
0
84
0
% R
% Ser:
9
0
0
0
0
0
0
0
0
0
9
34
0
0
0
% S
% Thr:
0
0
0
0
50
0
0
34
9
100
0
9
17
0
0
% T
% Val:
0
0
9
0
0
100
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _