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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V0A4
All Species:
6.06
Human Site:
T681
Identified Species:
12.12
UniProt:
Q9HBG4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBG4
NP_065683.2
840
96358
T681
S
R
I
Q
E
D
A
T
E
N
I
E
G
D
S
Chimpanzee
Pan troglodytes
XP_511508
838
96562
R684
T
L
N
F
G
G
I
R
V
G
N
G
P
T
E
Rhesus Macaque
Macaca mulatta
XP_001105743
987
112668
T830
S
R
I
Q
E
D
A
T
E
N
I
E
G
D
S
Dog
Lupus familis
XP_539895
839
96055
E681
S
M
M
Q
N
A
T
E
D
V
E
G
D
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q920R6
833
95587
V681
F
T
I
H
E
D
A
V
E
G
D
H
S
G
H
Rat
Rattus norvegicus
P25286
838
96309
R678
T
L
N
F
G
G
I
R
V
G
N
G
P
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9I8D0
838
95966
R678
T
H
N
F
G
G
I
R
V
G
N
G
P
T
E
Frog
Xenopus laevis
Q8AVM5
831
95538
R677
T
H
N
F
G
G
I
R
V
G
N
G
P
T
E
Zebra Danio
Brachydanio rerio
NP_001018502
839
95617
R679
T
Q
K
F
G
G
V
R
V
G
N
G
P
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P30628
905
103383
Q725
F
L
Y
R
R
D
K
Q
Q
S
R
Y
S
T
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32563
840
95510
S687
L
E
A
Q
Q
L
I
S
A
M
D
A
D
D
A
Red Bread Mold
Neurospora crassa
Q01290
856
97974
E694
S
R
V
S
A
L
D
E
D
D
E
E
D
P
S
Conservation
Percent
Protein Identity:
100
61.9
83.5
90.9
N.A.
85.8
62.2
N.A.
N.A.
61.3
61.4
60.5
N.A.
N.A.
N.A.
51.1
N.A.
Protein Similarity:
100
77.3
84.3
95.4
N.A.
91.9
76.9
N.A.
N.A.
76.6
77
76.3
N.A.
N.A.
N.A.
66.9
N.A.
P-Site Identity:
100
0
100
20
N.A.
33.3
0
N.A.
N.A.
0
0
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
6.6
100
40
N.A.
33.3
6.6
N.A.
N.A.
6.6
6.6
13.3
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
39.5
41.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
59.4
60.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
9
25
0
9
0
0
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
34
9
0
17
9
17
0
25
25
0
% D
% Glu:
0
9
0
0
25
0
0
17
25
0
17
25
0
0
42
% E
% Phe:
17
0
0
42
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
42
42
0
0
0
50
0
50
17
9
0
% G
% His:
0
17
0
9
0
0
0
0
0
0
0
9
0
0
9
% H
% Ile:
0
0
25
0
0
0
42
0
0
0
17
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
9
25
0
0
0
17
0
0
0
0
0
0
0
0
9
% L
% Met:
0
9
9
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
34
0
9
0
0
0
0
17
42
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
42
9
0
% P
% Gln:
0
9
0
34
9
0
0
9
9
0
0
0
0
0
0
% Q
% Arg:
0
25
0
9
9
0
0
42
0
0
9
0
0
0
0
% R
% Ser:
34
0
0
9
0
0
0
9
0
9
0
0
17
0
34
% S
% Thr:
42
9
0
0
0
0
9
17
0
0
0
0
0
50
0
% T
% Val:
0
0
9
0
0
0
9
9
42
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _