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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDF All Species: 5.45
Human Site: T33 Identified Species: 15
UniProt: Q9HBH1 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBH1 NP_071736.1 243 27013 T33 G V R A C S S T A A P D G V E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_853641 242 26864 A32 G G R A C S S A P A R D G L E
Cat Felis silvestris
Mouse Mus musculus NP_080789 231 25761 Y36 G P A R T R S Y W R Y L R R L
Rat Rattus norvegicus XP_002725458 231 25861 T33 S L E G A A R T R S Y W R Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001108286 240 26702 R30 P N V T H V P R R L S S S S W
Zebra Danio Brachydanio rerio NP_001028902 247 27573 T37 P L S A N T C T A S P R T H S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_731494 238 27102 K32 P A N Q S F R K W Y Q H L W T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790987 186 20983 H25 R G K S D P V H P Q D I R T K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FV53 259 28895 S48 Y N L P T S S S S S L S T K A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 78.5 N.A. 76.1 73.2 N.A. N.A. N.A. 50.2 46.9 N.A. 37.8 N.A. N.A. 37.4
Protein Similarity: 100 N.A. N.A. 82.7 N.A. 80.2 79.4 N.A. N.A. N.A. 65.4 64.3 N.A. 53.9 N.A. N.A. 49.3
P-Site Identity: 100 N.A. N.A. 66.6 N.A. 13.3 6.6 N.A. N.A. N.A. 0 26.6 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 N.A. N.A. 73.3 N.A. 13.3 26.6 N.A. N.A. N.A. 0 46.6 N.A. 0 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 33.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 48.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 12 34 12 12 0 12 23 23 0 0 0 0 12 % A
% Cys: 0 0 0 0 23 0 12 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 12 0 0 0 0 0 12 23 0 0 0 % D
% Glu: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 23 % E
% Phe: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % F
% Gly: 34 23 0 12 0 0 0 0 0 0 0 0 23 0 0 % G
% His: 0 0 0 0 12 0 0 12 0 0 0 12 0 12 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % I
% Lys: 0 0 12 0 0 0 0 12 0 0 0 0 0 12 12 % K
% Leu: 0 23 12 0 0 0 0 0 0 12 12 12 12 12 23 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 23 12 0 12 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 34 12 0 12 0 12 12 0 23 0 23 0 0 0 0 % P
% Gln: 0 0 0 12 0 0 0 0 0 12 12 0 0 0 0 % Q
% Arg: 12 0 23 12 0 12 23 12 23 12 12 12 34 12 0 % R
% Ser: 12 0 12 12 12 34 45 12 12 34 12 23 12 12 12 % S
% Thr: 0 0 0 12 23 12 0 34 0 0 0 0 23 12 12 % T
% Val: 0 12 12 0 0 12 12 0 0 0 0 0 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 23 0 0 12 0 12 12 % W
% Tyr: 12 0 0 0 0 0 0 12 0 12 23 0 0 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _