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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDF All Species: 9.7
Human Site: Y48 Identified Species: 26.67
UniProt: Q9HBH1 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBH1 NP_071736.1 243 27013 Y48 G P A L R R S Y W R H L R R L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_853641 242 26864 Y47 G P A R Q R S Y W R Y V R R L
Cat Felis silvestris
Mouse Mus musculus NP_080789 231 25761 P51 V C G A P Q P P Y A H V C Q V
Rat Rattus norvegicus XP_002725458 231 25861 P48 R R L V R G A P Q P P Y T R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001108286 240 26702 Y45 T L G K K R S Y W R Y L R R R
Zebra Danio Brachydanio rerio NP_001028902 247 27573 Y52 T N V K V R S Y L Q Y M K R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_731494 238 27102 P47 T E R T N L P P Y N H F T Q I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790987 186 20983 K40 E F Q D L I Q K M V G V M R K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FV53 259 28895 E63 G W L L G L G E K K K K V D L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 78.5 N.A. 76.1 73.2 N.A. N.A. N.A. 50.2 46.9 N.A. 37.8 N.A. N.A. 37.4
Protein Similarity: 100 N.A. N.A. 82.7 N.A. 80.2 79.4 N.A. N.A. N.A. 65.4 64.3 N.A. 53.9 N.A. N.A. 49.3
P-Site Identity: 100 N.A. N.A. 73.3 N.A. 6.6 13.3 N.A. N.A. N.A. 53.3 26.6 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 40 33.3 N.A. N.A. N.A. 66.6 53.3 N.A. 26.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 33.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 48.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 23 12 0 0 12 0 0 12 0 0 0 0 0 % A
% Cys: 0 12 0 0 0 0 0 0 0 0 0 0 12 0 0 % C
% Asp: 0 0 0 12 0 0 0 0 0 0 0 0 0 12 0 % D
% Glu: 12 12 0 0 0 0 0 12 0 0 0 0 0 0 0 % E
% Phe: 0 12 0 0 0 0 0 0 0 0 0 12 0 0 0 % F
% Gly: 34 0 23 0 12 12 12 0 0 0 12 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 34 0 0 0 0 % H
% Ile: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 12 % I
% Lys: 0 0 0 23 12 0 0 12 12 12 12 12 12 0 23 % K
% Leu: 0 12 23 23 12 23 0 0 12 0 0 23 0 0 34 % L
% Met: 0 0 0 0 0 0 0 0 12 0 0 12 12 0 0 % M
% Asn: 0 12 0 0 12 0 0 0 0 12 0 0 0 0 0 % N
% Pro: 0 23 0 0 12 0 23 34 0 12 12 0 0 0 0 % P
% Gln: 0 0 12 0 12 12 12 0 12 12 0 0 0 23 0 % Q
% Arg: 12 12 12 12 23 45 0 0 0 34 0 0 34 67 12 % R
% Ser: 0 0 0 0 0 0 45 0 0 0 0 0 0 0 0 % S
% Thr: 34 0 0 12 0 0 0 0 0 0 0 0 23 0 0 % T
% Val: 12 0 12 12 12 0 0 0 0 12 0 34 12 0 23 % V
% Trp: 0 12 0 0 0 0 0 0 34 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 45 23 0 34 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _