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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKNK2
All Species:
10
Human Site:
S43
Identified Species:
20
UniProt:
Q9HBH9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBH9
NP_060042.2
465
51875
S43
S
D
F
G
L
Q
C
S
A
R
P
D
M
P
A
Chimpanzee
Pan troglodytes
XP_512248
805
84821
P40
C
V
L
V
A
L
L
P
A
S
G
I
P
L
S
Rhesus Macaque
Macaca mulatta
XP_001117579
489
54064
S67
S
D
F
G
L
Q
C
S
A
R
P
D
M
P
A
Dog
Lupus familis
XP_855041
1044
109683
L632
T
G
E
T
G
F
S
L
E
C
P
A
R
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDB0
459
51614
E43
S
D
F
S
P
Q
C
E
A
R
P
D
M
P
S
Rat
Rattus norvegicus
Q5U2N4
459
51555
E43
S
D
F
S
P
Q
C
E
A
R
P
D
M
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235171
508
56331
C92
V
E
L
S
P
F
H
C
S
P
K
E
M
V
S
Frog
Xenopus laevis
Q6P431
467
52653
S43
V
F
N
F
D
C
P
S
R
P
D
V
P
S
S
Zebra Danio
Brachydanio rerio
NP_997888
472
52923
S43
S
S
F
I
L
E
R
S
T
R
P
A
M
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731624
1090
123424
N37
V
E
R
Q
A
E
L
N
R
H
K
E
E
M
Q
Honey Bee
Apis mellifera
XP_395927
516
58135
R37
E
E
A
R
R
K
R
R
K
K
K
R
S
G
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779905
511
56921
S69
A
D
E
T
C
L
L
S
E
Q
M
D
L
M
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.8
92.4
34.6
N.A.
92.6
92.6
N.A.
N.A.
60.8
76.8
73.3
N.A.
24
49.8
N.A.
48.7
Protein Similarity:
100
48.5
93.4
36.8
N.A.
95.2
95.2
N.A.
N.A.
73
87.7
84.5
N.A.
31
66.6
N.A.
64.5
P-Site Identity:
100
6.6
100
13.3
N.A.
73.3
73.3
N.A.
N.A.
6.6
6.6
53.3
N.A.
0
0
N.A.
20
P-Site Similarity:
100
13.3
100
20
N.A.
80
80
N.A.
N.A.
33.3
13.3
66.6
N.A.
26.6
26.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
17
0
0
0
42
0
0
17
0
0
17
% A
% Cys:
9
0
0
0
9
9
34
9
0
9
0
0
0
0
0
% C
% Asp:
0
42
0
0
9
0
0
0
0
0
9
42
0
0
9
% D
% Glu:
9
25
17
0
0
17
0
17
17
0
0
17
9
0
0
% E
% Phe:
0
9
42
9
0
17
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
17
9
0
0
0
0
0
9
0
0
9
0
% G
% His:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
9
0
0
9
9
25
0
0
0
0
% K
% Leu:
0
0
17
0
25
17
25
9
0
0
0
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
50
17
9
% M
% Asn:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
25
0
9
9
0
17
50
0
17
50
0
% P
% Gln:
0
0
0
9
0
34
0
0
0
9
0
0
0
0
9
% Q
% Arg:
0
0
9
9
9
0
17
9
17
42
0
9
9
0
0
% R
% Ser:
42
9
0
25
0
0
9
42
9
9
0
0
9
9
59
% S
% Thr:
9
0
0
17
0
0
0
0
9
0
0
0
0
0
0
% T
% Val:
25
9
0
9
0
0
0
0
0
0
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _