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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MKNK2 All Species: 46.97
Human Site: Y272 Identified Species: 93.94
UniProt: Q9HBH9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBH9 NP_060042.2 465 51875 Y272 F S E E A S I Y D K R C D L W
Chimpanzee Pan troglodytes XP_512248 805 84821 Y599 F S E E A S I Y D K R C D L W
Rhesus Macaque Macaca mulatta XP_001117579 489 54064 Y296 F S E E A S I Y D K R C D L W
Dog Lupus familis XP_855041 1044 109683 Y864 F S E E A S I Y D K R C D L W
Cat Felis silvestris
Mouse Mus musculus Q8CDB0 459 51614 Y272 F S E E A S I Y D K R C D L W
Rat Rattus norvegicus Q5U2N4 459 51555 Y272 F S E E A S I Y D K R C D L W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001235171 508 56331 Y320 F T E E A T F Y D K R C D L W
Frog Xenopus laevis Q6P431 467 52653 Y271 F N E E A S I Y D K R C D L W
Zebra Danio Brachydanio rerio NP_997888 472 52923 Y272 F N E E A S I Y D K R C D L W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_731624 1090 123424 Y255 F V G E A H Y Y D K R C D L W
Honey Bee Apis mellifera XP_395927 516 58135 Y245 F I G E A N Y Y D K R C D L W
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_779905 511 56921 Y306 Y D L Q A T V Y D K R C D L W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 42.8 92.4 34.6 N.A. 92.6 92.6 N.A. N.A. 60.8 76.8 73.3 N.A. 24 49.8 N.A. 48.7
Protein Similarity: 100 48.5 93.4 36.8 N.A. 95.2 95.2 N.A. N.A. 73 87.7 84.5 N.A. 31 66.6 N.A. 64.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 80 93.3 93.3 N.A. 73.3 73.3 N.A. 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 100 100 N.A. 73.3 80 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 100 0 0 0 100 0 0 % D
% Glu: 0 0 75 92 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 92 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 0 67 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % K
% Leu: 0 0 9 0 0 0 0 0 0 0 0 0 0 100 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 17 0 0 0 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % R
% Ser: 0 50 0 0 0 67 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 9 0 0 0 17 0 0 0 0 0 0 0 0 0 % T
% Val: 0 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % W
% Tyr: 9 0 0 0 0 0 17 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _