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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARVB All Species: 37.27
Human Site: S173 Identified Species: 63.08
UniProt: Q9HBI1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBI1 NP_001003828.1 364 41714 S173 A L R W S V D S I H G K N L V
Chimpanzee Pan troglodytes XP_001171467 372 42228 S181 S I K W N V D S V H A K S L V
Rhesus Macaque Macaca mulatta XP_001106273 282 31975 I106 A E V T Q S E I G Q K Q K L Q
Dog Lupus familis XP_538336 393 44396 S202 A L Q W T V D S I H G K N L V
Cat Felis silvestris
Mouse Mus musculus Q9ES46 365 41651 S174 P L R W N V D S I H G K N L V
Rat Rattus norvegicus Q9HB97 372 42273 S181 S I K W N V D S V H A K N L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519401 299 34345 T123 A T L H L L I T L V T H F Q A
Chicken Gallus gallus XP_416459 365 41865 S174 T I K W N V D S I H G K N L I
Frog Xenopus laevis NP_001089519 365 41596 S174 A I R W N V D S I H G K N L V
Zebra Danio Brachydanio rerio NP_956020 365 41402 S173 N T E W S V D S I H S K N L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608352 367 41845 S176 I P K W S V A S V H S K N I V
Honey Bee Apis mellifera XP_393249 365 41734 S174 P Y K W H V E S V H S K N I V
Nematode Worm Caenorhab. elegans O16785 375 42983 L185 Q E K W S A D L I H Q K D F T
Sea Urchin Strong. purpuratus XP_785434 360 41100 A169 K D K W S V D A I H S R N L V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.1 70.3 81.4 N.A. 92 73.6 N.A. 62.6 90.9 85.4 74.5 N.A. 58.8 63.2 47.2 61.2
Protein Similarity: 100 85.4 71.6 86.5 N.A. 96.9 85.4 N.A. 72.5 96.7 93.9 87.9 N.A. 74.3 79.4 67.4 79.4
P-Site Identity: 100 53.3 13.3 86.6 N.A. 86.6 60 N.A. 6.6 66.6 86.6 73.3 N.A. 53.3 46.6 40 60
P-Site Similarity: 100 93.3 26.6 100 N.A. 93.3 93.3 N.A. 26.6 93.3 100 73.3 N.A. 73.3 73.3 53.3 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 36 0 0 0 0 8 8 8 0 0 15 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 72 0 0 0 0 0 8 0 0 % D
% Glu: 0 15 8 0 0 0 15 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 36 0 0 0 0 % G
% His: 0 0 0 8 8 0 0 0 0 86 0 8 0 0 0 % H
% Ile: 8 29 0 0 0 0 8 8 58 0 0 0 0 15 8 % I
% Lys: 8 0 50 0 0 0 0 0 0 0 8 79 8 0 0 % K
% Leu: 0 22 8 0 8 8 0 8 8 0 0 0 0 72 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 36 0 0 0 0 0 0 0 72 0 0 % N
% Pro: 15 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 8 0 8 0 0 0 0 8 8 8 0 8 8 % Q
% Arg: 0 0 22 0 0 0 0 0 0 0 0 8 0 0 0 % R
% Ser: 15 0 0 0 36 8 0 72 0 0 29 0 8 0 0 % S
% Thr: 8 15 0 8 8 0 0 8 0 0 8 0 0 0 8 % T
% Val: 0 0 8 0 0 79 0 0 29 8 0 0 0 0 72 % V
% Trp: 0 0 0 86 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _