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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARVB All Species: 21.52
Human Site: S223 Identified Species: 36.41
UniProt: Q9HBI1 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBI1 NP_001003828.1 364 41714 S223 L L H S S H I S E E L T T T T
Chimpanzee Pan troglodytes XP_001171467 372 42228 Q231 I L Q S R Q I Q E E I T G N T
Rhesus Macaque Macaca mulatta XP_001106273 282 31975 H155 L L V S L A M H F R A P I R L
Dog Lupus familis XP_538336 393 44396 T252 L L H S S H V T E E L T T T T
Cat Felis silvestris
Mouse Mus musculus Q9ES46 365 41651 S224 L L H S S H I S E E L T T T T
Rat Rattus norvegicus Q9HB97 372 42273 Q231 I L Q S R Q I Q E E I T G N T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519401 299 34345 S172 M E M M M G R S K R D A M D T
Chicken Gallus gallus XP_416459 365 41865 T224 L L Q T T H V T E E L T T T T
Frog Xenopus laevis NP_001089519 365 41596 T224 L L Q T A H V T E E L T T T T
Zebra Danio Brachydanio rerio NP_956020 365 41402 K224 L Q T A H V T K Q L T S T T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608352 367 41845 Q226 V L N A Q K F Q E Q I T S E Y
Honey Bee Apis mellifera XP_393249 365 41734 R224 Q L T H N T I R E E I T S T Y
Nematode Worm Caenorhab. elegans O16785 375 42983 T235 Q V K T H R I T E Q I T T V Q
Sea Urchin Strong. purpuratus XP_785434 360 41100 E219 M L Q T S R V E E E I T A T N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.1 70.3 81.4 N.A. 92 73.6 N.A. 62.6 90.9 85.4 74.5 N.A. 58.8 63.2 47.2 61.2
Protein Similarity: 100 85.4 71.6 86.5 N.A. 96.9 85.4 N.A. 72.5 96.7 93.9 87.9 N.A. 74.3 79.4 67.4 79.4
P-Site Identity: 100 46.6 20 86.6 N.A. 100 46.6 N.A. 13.3 66.6 66.6 26.6 N.A. 20 40 26.6 40
P-Site Similarity: 100 60 26.6 100 N.A. 100 60 N.A. 26.6 93.3 93.3 46.6 N.A. 60 60 60 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 15 8 8 0 0 0 0 8 8 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % D
% Glu: 0 8 0 0 0 0 0 8 79 65 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 0 0 0 0 0 15 0 0 % G
% His: 0 0 22 8 15 36 0 8 0 0 0 0 0 0 0 % H
% Ile: 15 0 0 0 0 0 43 0 0 0 43 0 8 0 0 % I
% Lys: 0 0 8 0 0 8 0 8 8 0 0 0 0 0 0 % K
% Leu: 50 79 0 0 8 0 0 0 0 8 36 0 0 0 8 % L
% Met: 15 0 8 8 8 0 8 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 8 0 8 0 0 0 0 0 0 0 0 15 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % P
% Gln: 15 8 36 0 8 15 0 22 8 15 0 0 0 0 8 % Q
% Arg: 0 0 0 0 15 15 8 8 0 15 0 0 0 8 0 % R
% Ser: 0 0 0 43 29 0 0 22 0 0 0 8 15 0 0 % S
% Thr: 0 0 15 29 8 8 8 29 0 0 8 79 50 58 65 % T
% Val: 8 8 8 0 0 8 29 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _