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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARVB All Species: 14.55
Human Site: S254 Identified Species: 24.62
UniProt: Q9HBI1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBI1 NP_001003828.1 364 41714 S254 D H A P D K L S V V K K S L I
Chimpanzee Pan troglodytes XP_001171467 372 42228 N262 D H A P D K L N V V K K T L I
Rhesus Macaque Macaca mulatta XP_001106273 282 31975 S186 L L H S S H I S E E L T T T T
Dog Lupus familis XP_538336 393 44396 S283 D H A P D K L S V V K K S L I
Cat Felis silvestris
Mouse Mus musculus Q9ES46 365 41651 N255 D H A P D K L N L V K K S L I
Rat Rattus norvegicus Q9HB97 372 42273 N262 D H A P D K L N V V K K T L I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519401 299 34345 L203 I I F V N K H L N K L N L E V
Chicken Gallus gallus XP_416459 365 41865 S255 D H A P D K L S V V K K S L I
Frog Xenopus laevis NP_001089519 365 41596 S255 D H A P D K L S V V K K S L I
Zebra Danio Brachydanio rerio NP_956020 365 41402 N255 D H A P D K L N V V K T S L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608352 367 41845 A257 D C A P D K L A V V K K S L I
Honey Bee Apis mellifera XP_393249 365 41734 A255 D H P A D K L A V V K K S L V
Nematode Worm Caenorhab. elegans O16785 375 42983 A266 D Y G P D K L A H V K T S L L
Sea Urchin Strong. purpuratus XP_785434 360 41100 N250 D H A P D K L N V V K K S L I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.1 70.3 81.4 N.A. 92 73.6 N.A. 62.6 90.9 85.4 74.5 N.A. 58.8 63.2 47.2 61.2
Protein Similarity: 100 85.4 71.6 86.5 N.A. 96.9 85.4 N.A. 72.5 96.7 93.9 87.9 N.A. 74.3 79.4 67.4 79.4
P-Site Identity: 100 86.6 6.6 100 N.A. 86.6 86.6 N.A. 6.6 100 100 86.6 N.A. 86.6 73.3 60 93.3
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 20 100 100 93.3 N.A. 93.3 86.6 80 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 72 8 0 0 0 22 0 0 0 0 0 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 86 0 0 0 86 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 8 8 0 0 0 8 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 72 8 0 0 8 8 0 8 0 0 0 0 0 0 % H
% Ile: 8 8 0 0 0 0 8 0 0 0 0 0 0 0 72 % I
% Lys: 0 0 0 0 0 93 0 0 0 8 86 72 0 0 0 % K
% Leu: 8 8 0 0 0 0 86 8 8 0 15 0 8 86 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 36 8 0 0 8 0 0 0 % N
% Pro: 0 0 8 79 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 8 8 0 0 36 0 0 0 0 72 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 22 22 8 8 % T
% Val: 0 0 0 8 0 0 0 0 72 86 0 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _