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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARVB All Species: 34.55
Human Site: S80 Identified Species: 58.46
UniProt: Q9HBI1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBI1 NP_001003828.1 364 41714 S80 R T M I D P T S K E D P K F K
Chimpanzee Pan troglodytes XP_001171467 372 42228 S88 R T M V D P N S R S D P K L Q
Rhesus Macaque Macaca mulatta XP_001106273 282 31975 D46 I D P T S K E D P K F K E L V
Dog Lupus familis XP_538336 393 44396 S109 R T M I D P T S K D D P K F K
Cat Felis silvestris
Mouse Mus musculus Q9ES46 365 41651 S81 R T M I D P T S R E D P K F K
Rat Rattus norvegicus Q9HB97 372 42273 S88 R T M V D P N S R N D P K L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519401 299 34345 L63 L H K L L E K L S G L K L S V
Chicken Gallus gallus XP_416459 365 41865 S81 R T M I D P N S K E D P K F K
Frog Xenopus laevis NP_001089519 365 41596 S81 R T M I D P N S K E E T K F K
Zebra Danio Brachydanio rerio NP_956020 365 41402 S80 R T I L D P T S R E D L N F K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608352 367 41845 S83 R A V I D P Q S I S D P Q V I
Honey Bee Apis mellifera XP_393249 365 41734 S82 R S M I E P R S L E D S K L K
Nematode Worm Caenorhab. elegans O16785 375 42983 E80 L A R N I W L E E G E I R R Y
Sea Urchin Strong. purpuratus XP_785434 360 41100 K80 P D S K D S P K V K E L S E V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.1 70.3 81.4 N.A. 92 73.6 N.A. 62.6 90.9 85.4 74.5 N.A. 58.8 63.2 47.2 61.2
Protein Similarity: 100 85.4 71.6 86.5 N.A. 96.9 85.4 N.A. 72.5 96.7 93.9 87.9 N.A. 74.3 79.4 67.4 79.4
P-Site Identity: 100 60 0 93.3 N.A. 93.3 60 N.A. 0 93.3 80 66.6 N.A. 46.6 60 0 6.6
P-Site Similarity: 100 80 13.3 100 N.A. 100 80 N.A. 6.6 93.3 86.6 86.6 N.A. 60 73.3 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 0 0 72 0 0 8 0 8 65 0 0 0 0 % D
% Glu: 0 0 0 0 8 8 8 8 8 43 22 0 8 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 43 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 8 50 8 0 0 0 8 0 0 8 0 0 8 % I
% Lys: 0 0 8 8 0 8 8 8 29 15 0 15 58 0 50 % K
% Leu: 15 0 0 15 8 0 8 8 8 0 8 15 8 29 0 % L
% Met: 0 0 58 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 29 0 0 8 0 0 8 0 0 % N
% Pro: 8 0 8 0 0 72 8 0 8 0 0 50 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 15 % Q
% Arg: 72 0 8 0 0 0 8 0 29 0 0 0 8 8 0 % R
% Ser: 0 8 8 0 8 8 0 72 8 15 0 8 8 8 0 % S
% Thr: 0 58 0 8 0 0 29 0 0 0 0 8 0 0 0 % T
% Val: 0 0 8 15 0 0 0 0 8 0 0 0 0 8 22 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _