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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARVB All Species: 36.06
Human Site: T227 Identified Species: 61.03
UniProt: Q9HBI1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBI1 NP_001003828.1 364 41714 T227 S H I S E E L T T T T E M M M
Chimpanzee Pan troglodytes XP_001171467 372 42228 T235 R Q I Q E E I T G N T E A L S
Rhesus Macaque Macaca mulatta XP_001106273 282 31975 P159 L A M H F R A P I R L P E H V
Dog Lupus familis XP_538336 393 44396 T256 S H V T E E L T T T T E M M M
Cat Felis silvestris
Mouse Mus musculus Q9ES46 365 41651 T228 S H I S E E L T T T T E I M M
Rat Rattus norvegicus Q9HB97 372 42273 T235 R Q I Q E E I T G N T E A L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519401 299 34345 A176 M G R S K R D A M D T L F D H
Chicken Gallus gallus XP_416459 365 41865 T228 T H V T E E L T T T T E M M M
Frog Xenopus laevis NP_001089519 365 41596 T228 A H V T E E L T T T T E M M M
Zebra Danio Brachydanio rerio NP_956020 365 41402 S228 H V T K Q L T S T T T E M M I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608352 367 41845 T230 Q K F Q E Q I T S E Y D D L G
Honey Bee Apis mellifera XP_393249 365 41734 T228 N T I R E E I T S T Y D D L G
Nematode Worm Caenorhab. elegans O16785 375 42983 T239 H R I T E Q I T T V Q T E L A
Sea Urchin Strong. purpuratus XP_785434 360 41100 T223 S R V E E E I T A T N E A I G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.1 70.3 81.4 N.A. 92 73.6 N.A. 62.6 90.9 85.4 74.5 N.A. 58.8 63.2 47.2 61.2
Protein Similarity: 100 85.4 71.6 86.5 N.A. 96.9 85.4 N.A. 72.5 96.7 93.9 87.9 N.A. 74.3 79.4 67.4 79.4
P-Site Identity: 100 40 0 86.6 N.A. 93.3 40 N.A. 13.3 80 80 40 N.A. 13.3 33.3 26.6 40
P-Site Similarity: 100 53.3 13.3 100 N.A. 100 53.3 N.A. 20 100 100 60 N.A. 46.6 66.6 53.3 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 0 8 8 8 0 0 0 22 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 8 0 15 15 8 0 % D
% Glu: 0 0 0 8 79 65 0 0 0 8 0 65 15 0 0 % E
% Phe: 0 0 8 0 8 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 8 0 0 0 0 0 0 15 0 0 0 0 0 22 % G
% His: 15 36 0 8 0 0 0 0 0 0 0 0 0 8 8 % H
% Ile: 0 0 43 0 0 0 43 0 8 0 0 0 8 8 8 % I
% Lys: 0 8 0 8 8 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 0 0 0 8 36 0 0 0 8 8 0 36 0 % L
% Met: 8 0 8 0 0 0 0 0 8 0 0 0 36 43 36 % M
% Asn: 8 0 0 0 0 0 0 0 0 15 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % P
% Gln: 8 15 0 22 8 15 0 0 0 0 8 0 0 0 0 % Q
% Arg: 15 15 8 8 0 15 0 0 0 8 0 0 0 0 0 % R
% Ser: 29 0 0 22 0 0 0 8 15 0 0 0 0 0 15 % S
% Thr: 8 8 8 29 0 0 8 79 50 58 65 8 0 0 0 % T
% Val: 0 8 29 0 0 0 0 0 0 8 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _