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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARVB All Species: 28.48
Human Site: T228 Identified Species: 48.21
UniProt: Q9HBI1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBI1 NP_001003828.1 364 41714 T228 H I S E E L T T T T E M M M G
Chimpanzee Pan troglodytes XP_001171467 372 42228 G236 Q I Q E E I T G N T E A L S G
Rhesus Macaque Macaca mulatta XP_001106273 282 31975 I160 A M H F R A P I R L P E H V T
Dog Lupus familis XP_538336 393 44396 T257 H V T E E L T T T T E M M M G
Cat Felis silvestris
Mouse Mus musculus Q9ES46 365 41651 T229 H I S E E L T T T T E I M M G
Rat Rattus norvegicus Q9HB97 372 42273 G236 Q I Q E E I T G N T E A L S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519401 299 34345 M177 G R S K R D A M D T L F D H A
Chicken Gallus gallus XP_416459 365 41865 T229 H V T E E L T T T T E M M M G
Frog Xenopus laevis NP_001089519 365 41596 T229 H V T E E L T T T T E M M M G
Zebra Danio Brachydanio rerio NP_956020 365 41402 T229 V T K Q L T S T T T E M M I G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608352 367 41845 S231 K F Q E Q I T S E Y D D L G M
Honey Bee Apis mellifera XP_393249 365 41734 S229 T I R E E I T S T Y D D L G M
Nematode Worm Caenorhab. elegans O16785 375 42983 T240 R I T E Q I T T V Q T E L A P
Sea Urchin Strong. purpuratus XP_785434 360 41100 A224 R V E E E I T A T N E A I G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.1 70.3 81.4 N.A. 92 73.6 N.A. 62.6 90.9 85.4 74.5 N.A. 58.8 63.2 47.2 61.2
Protein Similarity: 100 85.4 71.6 86.5 N.A. 96.9 85.4 N.A. 72.5 96.7 93.9 87.9 N.A. 74.3 79.4 67.4 79.4
P-Site Identity: 100 46.6 0 86.6 N.A. 93.3 46.6 N.A. 13.3 86.6 86.6 46.6 N.A. 13.3 33.3 26.6 40
P-Site Similarity: 100 60 13.3 100 N.A. 100 60 N.A. 20 100 100 66.6 N.A. 46.6 60 53.3 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 8 8 8 0 0 0 22 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 8 0 15 15 8 0 0 % D
% Glu: 0 0 8 79 65 0 0 0 8 0 65 15 0 0 0 % E
% Phe: 0 8 0 8 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 8 0 0 0 0 0 0 15 0 0 0 0 0 22 65 % G
% His: 36 0 8 0 0 0 0 0 0 0 0 0 8 8 0 % H
% Ile: 0 43 0 0 0 43 0 8 0 0 0 8 8 8 0 % I
% Lys: 8 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 8 36 0 0 0 8 8 0 36 0 0 % L
% Met: 0 8 0 0 0 0 0 8 0 0 0 36 43 36 15 % M
% Asn: 0 0 0 0 0 0 0 0 15 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 8 % P
% Gln: 15 0 22 8 15 0 0 0 0 8 0 0 0 0 0 % Q
% Arg: 15 8 8 0 15 0 0 0 8 0 0 0 0 0 0 % R
% Ser: 0 0 22 0 0 0 8 15 0 0 0 0 0 15 0 % S
% Thr: 8 8 29 0 0 8 79 50 58 65 8 0 0 0 8 % T
% Val: 8 29 0 0 0 0 0 0 8 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _