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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C9orf46 All Species: 22.73
Human Site: S119 Identified Species: 62.5
UniProt: Q9HBL7 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBL7 NP_060935.1 147 17201 S119 D I L E T E K S K L Q L P R G
Chimpanzee Pan troglodytes XP_520475 147 17183 S119 D I L E T E K S K L Q L P R G
Rhesus Macaque Macaca mulatta XP_001081989 147 17162 S119 D I L E T E K S K L Q L P R G
Dog Lupus familis XP_852078 147 17395 S119 N I L E T E K S K L Q L P R G
Cat Felis silvestris
Mouse Mus musculus Q9D3P8 147 17243 T119 D I L E T E K T K L E L P K G
Rat Rattus norvegicus NP_001099817 147 17294 T119 D I L E T E K T K L E L P K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505826 156 18090 D128 N I L E A E N D K L Q L P K G
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001028270 149 17121 E119 S I M V S E C E R L D V P H G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796465 113 12699 E86 A E R I L N E E P S I L A L P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 97.9 89.8 N.A. 82.3 85.7 N.A. 60.9 N.A. N.A. 61.7 N.A. N.A. N.A. N.A. 33.3
Protein Similarity: 100 100 99.3 98.6 N.A. 93.1 96.5 N.A. 75 N.A. N.A. 79.8 N.A. N.A. N.A. N.A. 51
P-Site Identity: 100 100 100 93.3 N.A. 80 80 N.A. 66.6 N.A. N.A. 33.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 80 N.A. N.A. 60 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 12 0 0 0 0 0 0 0 12 0 0 % A
% Cys: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % C
% Asp: 56 0 0 0 0 0 0 12 0 0 12 0 0 0 0 % D
% Glu: 0 12 0 78 0 89 12 23 0 0 23 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % H
% Ile: 0 89 0 12 0 0 0 0 0 0 12 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 67 0 78 0 0 0 0 34 0 % K
% Leu: 0 0 78 0 12 0 0 0 0 89 0 89 0 12 0 % L
% Met: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 23 0 0 0 0 12 12 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 12 0 0 0 89 0 12 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 56 0 0 0 0 % Q
% Arg: 0 0 12 0 0 0 0 0 12 0 0 0 0 45 0 % R
% Ser: 12 0 0 0 12 0 0 45 0 12 0 0 0 0 0 % S
% Thr: 0 0 0 0 67 0 0 23 0 0 0 0 0 0 0 % T
% Val: 0 0 0 12 0 0 0 0 0 0 0 12 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _