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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C9orf46
All Species:
22.73
Human Site:
S119
Identified Species:
62.5
UniProt:
Q9HBL7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBL7
NP_060935.1
147
17201
S119
D
I
L
E
T
E
K
S
K
L
Q
L
P
R
G
Chimpanzee
Pan troglodytes
XP_520475
147
17183
S119
D
I
L
E
T
E
K
S
K
L
Q
L
P
R
G
Rhesus Macaque
Macaca mulatta
XP_001081989
147
17162
S119
D
I
L
E
T
E
K
S
K
L
Q
L
P
R
G
Dog
Lupus familis
XP_852078
147
17395
S119
N
I
L
E
T
E
K
S
K
L
Q
L
P
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D3P8
147
17243
T119
D
I
L
E
T
E
K
T
K
L
E
L
P
K
G
Rat
Rattus norvegicus
NP_001099817
147
17294
T119
D
I
L
E
T
E
K
T
K
L
E
L
P
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505826
156
18090
D128
N
I
L
E
A
E
N
D
K
L
Q
L
P
K
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001028270
149
17121
E119
S
I
M
V
S
E
C
E
R
L
D
V
P
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796465
113
12699
E86
A
E
R
I
L
N
E
E
P
S
I
L
A
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
97.9
89.8
N.A.
82.3
85.7
N.A.
60.9
N.A.
N.A.
61.7
N.A.
N.A.
N.A.
N.A.
33.3
Protein Similarity:
100
100
99.3
98.6
N.A.
93.1
96.5
N.A.
75
N.A.
N.A.
79.8
N.A.
N.A.
N.A.
N.A.
51
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
66.6
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
80
N.A.
N.A.
60
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
0
0
0
0
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
56
0
0
0
0
0
0
12
0
0
12
0
0
0
0
% D
% Glu:
0
12
0
78
0
89
12
23
0
0
23
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
89
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
89
0
12
0
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
67
0
78
0
0
0
0
34
0
% K
% Leu:
0
0
78
0
12
0
0
0
0
89
0
89
0
12
0
% L
% Met:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
23
0
0
0
0
12
12
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
12
0
0
0
89
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
56
0
0
0
0
% Q
% Arg:
0
0
12
0
0
0
0
0
12
0
0
0
0
45
0
% R
% Ser:
12
0
0
0
12
0
0
45
0
12
0
0
0
0
0
% S
% Thr:
0
0
0
0
67
0
0
23
0
0
0
0
0
0
0
% T
% Val:
0
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _