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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPC25
All Species:
24.24
Human Site:
S185
Identified Species:
59.26
UniProt:
Q9HBM1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBM1
NP_065726.1
224
26153
S185
E
A
R
D
Y
E
V
S
D
S
A
P
H
L
E
Chimpanzee
Pan troglodytes
XP_526099
224
26093
S185
E
A
R
D
Y
E
V
S
D
S
A
P
H
L
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545510
394
45317
S355
E
A
R
E
Y
E
V
S
D
S
S
P
H
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3UA16
226
26439
Y187
E
A
K
E
Y
E
V
Y
D
S
S
P
H
L
E
Rat
Rattus norvegicus
Q5M856
226
26171
S187
E
A
K
E
Y
E
V
S
D
C
S
P
H
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513854
231
27211
T192
E
E
G
N
Y
E
V
T
E
S
S
P
H
L
D
Chicken
Gallus gallus
XP_422018
234
27701
T192
E
Q
G
D
Y
E
V
T
S
C
T
P
P
L
D
Frog
Xenopus laevis
Q6SKR5
228
26686
A187
A
E
G
D
Y
E
V
A
G
C
D
P
P
L
E
Zebra Danio
Brachydanio rerio
NP_001116529
234
27434
I191
A
E
G
I
Y
H
I
I
S
C
D
P
P
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196956
240
27407
D203
N
S
Q
Y
Q
V
T
D
C
C
P
A
I
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
49.7
N.A.
73.8
78.3
N.A.
61
46.1
41.6
31.6
N.A.
N.A.
N.A.
N.A.
25.8
Protein Similarity:
100
99.1
N.A.
53.8
N.A.
88.5
89.3
N.A.
78.3
69.6
61.8
54.2
N.A.
N.A.
N.A.
N.A.
46.2
P-Site Identity:
100
100
N.A.
86.6
N.A.
73.3
73.3
N.A.
53.3
46.6
46.6
26.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
86.6
60
53.3
33.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
50
0
0
0
0
0
10
0
0
20
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
50
0
0
0
0
0
% C
% Asp:
0
0
0
40
0
0
0
10
50
0
20
0
0
10
20
% D
% Glu:
70
30
0
30
0
80
0
0
10
0
0
0
0
0
70
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
40
0
0
0
0
0
10
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
60
0
0
% H
% Ile:
0
0
0
10
0
0
10
10
0
0
0
0
10
0
0
% I
% Lys:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
90
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
90
30
0
0
% P
% Gln:
0
10
10
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
0
0
0
40
20
50
40
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
20
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
10
80
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
90
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _