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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LGR6
All Species:
2.12
Human Site:
S680
Identified Species:
5.83
UniProt:
Q9HBX8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBX8
NP_001017403.1
967
104298
S680
C
V
R
A
Y
G
K
S
P
S
L
G
S
V
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117499
911
100286
V656
I
F
A
S
E
S
S
V
F
L
L
T
L
A
A
Dog
Lupus familis
XP_848875
965
103312
A678
C
I
R
A
Y
G
K
A
P
A
L
S
S
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3UVD5
967
104249
A680
C
V
R
A
Y
G
K
A
P
S
P
G
S
V
R
Rat
Rattus norvegicus
Q9Z2H4
951
104120
S656
D
L
M
K
H
G
K
S
S
H
L
R
Q
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512452
917
101001
I656
Q
I
T
A
F
L
S
I
F
A
S
E
T
S
I
Chicken
Gallus gallus
XP_425441
909
100302
A651
L
S
I
F
A
S
E
A
S
I
F
L
L
T
L
Frog
Xenopus laevis
NP_001089881
955
105573
H659
D
I
I
K
K
E
K
H
Q
H
L
R
K
F
Q
Zebra Danio
Brachydanio rerio
A8WGA3
687
75758
W433
A
N
S
A
L
I
R
W
P
S
Q
Q
H
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
52.6
89.1
N.A.
90.1
46.5
N.A.
48.5
52.7
45.1
20.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
67.2
92.8
N.A.
93.5
59.8
N.A.
63.8
68.1
59.7
35
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
6.6
73.3
N.A.
86.6
26.6
N.A.
6.6
0
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
13.3
93.3
N.A.
93.3
46.6
N.A.
33.3
13.3
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
56
12
0
0
34
0
23
0
0
0
12
12
% A
% Cys:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
12
12
12
0
0
0
0
12
0
0
0
% E
% Phe:
0
12
0
12
12
0
0
0
23
0
12
0
0
34
0
% F
% Gly:
0
0
0
0
0
45
0
0
0
0
0
23
0
0
0
% G
% His:
0
0
0
0
12
0
0
12
0
23
0
0
12
0
0
% H
% Ile:
12
34
23
0
0
12
0
12
0
12
0
0
0
0
12
% I
% Lys:
0
0
0
23
12
0
56
0
0
0
0
0
12
0
0
% K
% Leu:
12
12
0
0
12
12
0
0
0
12
56
12
23
0
12
% L
% Met:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
45
0
12
0
0
0
12
% P
% Gln:
12
0
0
0
0
0
0
0
12
0
12
12
12
0
23
% Q
% Arg:
0
0
34
0
0
0
12
0
0
0
0
23
0
0
34
% R
% Ser:
0
12
12
12
0
23
23
23
23
34
12
12
34
12
0
% S
% Thr:
0
0
12
0
0
0
0
0
0
0
0
12
12
12
0
% T
% Val:
0
23
0
0
0
0
0
12
0
0
0
0
0
34
0
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _