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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGK2 All Species: 12.42
Human Site: S404 Identified Species: 22.78
UniProt: Q9HBY8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBY8 NP_057360.2 427 47604 S404 C T P D T V A S S S G A S S A
Chimpanzee Pan troglodytes XP_001142856 441 49512 S418 C T P D T V A S S S G A S S A
Rhesus Macaque Macaca mulatta XP_001083986 450 50817 S427 C T P D T V A S S S G A S S A
Dog Lupus familis XP_849801 431 48950 L407 R S P D S I L L T A S V K E A
Cat Felis silvestris
Mouse Mus musculus Q9QZS5 367 41341 G347 D T V A S S S G A S S A F L G
Rat Rattus norvegicus Q8R4U9 367 41343 G347 D T M S S S S G A S S A F L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511204 429 48309 S405 R T P D L T A S S S G T S S A
Chicken Gallus gallus Q6U1I9 432 48872 I408 Q S P D S I L I T A S V K E A
Frog Xenopus laevis Q6GLY8 434 49082 I410 Q S P D S I L I T A S I K E A
Zebra Danio Brachydanio rerio Q7ZTW4 433 48964 V409 C S P D S A L V T S S I T E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8INB9 611 68466 G574 P D P T G P L G S I A E E P L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q2PJ68 463 54273 Q440 P S S L A P Q Q L A V T H R D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P12688 680 76461 Q655 E Y L S E S V Q K Q F G G W T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.9 83.5 62.4 N.A. 81 80.5 N.A. 73.6 62 60.3 63.5 N.A. 33.8 N.A. 41.9 N.A.
Protein Similarity: 100 87.7 86.2 75.8 N.A. 83.6 83.3 N.A. 80.8 75.4 74.8 74.3 N.A. 45.3 N.A. 58.5 N.A.
P-Site Identity: 100 100 100 20 N.A. 20 20 N.A. 73.3 20 20 33.3 N.A. 13.3 N.A. 0 N.A.
P-Site Similarity: 100 100 100 53.3 N.A. 40 40 N.A. 73.3 53.3 53.3 60 N.A. 13.3 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 8 31 0 16 31 8 39 0 0 62 % A
% Cys: 31 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 8 0 62 0 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 8 0 0 0 8 0 0 0 0 0 0 8 8 31 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 16 0 0 % F
% Gly: 0 0 0 0 8 0 0 24 0 0 31 8 8 0 16 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 24 0 16 0 8 0 16 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 8 0 0 0 24 0 0 % K
% Leu: 0 0 8 8 8 0 39 8 8 0 0 0 0 16 8 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 16 0 70 0 0 16 0 0 0 0 0 0 0 8 0 % P
% Gln: 16 0 0 0 0 0 8 16 0 8 0 0 0 0 0 % Q
% Arg: 16 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % R
% Ser: 0 39 8 16 47 24 16 31 39 54 47 0 31 31 0 % S
% Thr: 0 47 0 8 24 8 0 0 31 0 0 16 8 0 8 % T
% Val: 0 0 8 0 0 24 8 8 0 0 8 16 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _