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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOD2
All Species:
9.7
Human Site:
T245
Identified Species:
23.7
UniProt:
Q9HC29
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HC29
NP_071445.1
1040
115283
T245
S
T
Y
D
G
A
E
T
L
C
L
E
D
I
Y
Chimpanzee
Pan troglodytes
NP_001098710
1040
115280
T245
S
T
Y
D
G
A
E
T
L
C
L
E
D
I
Y
Rhesus Macaque
Macaca mulatta
XP_001084287
1044
115626
T249
S
T
Y
D
G
A
E
T
L
C
L
E
D
I
Y
Dog
Lupus familis
XP_544412
1311
144400
N539
S
T
Y
D
G
A
E
N
L
C
L
E
E
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
NP_665856
1013
112760
L232
Y
T
E
N
I
L
E
L
Q
T
E
V
G
T
A
Rat
Rattus norvegicus
NP_001099642
932
103380
L232
Y
T
E
N
T
L
E
L
R
T
E
V
G
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519938
1017
112446
E231
V
Y
T
E
N
A
L
E
I
R
K
I
D
G
A
Chicken
Gallus gallus
XP_418777
951
108698
L229
S
L
W
A
K
K
Q
L
D
I
G
A
K
F
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697924
980
109500
R230
S
T
Y
G
G
T
G
R
F
S
L
D
D
I
Y
Tiger Blowfish
Takifugu rubipres
NP_001035913
989
110404
T230
F
L
S
T
Y
G
G
T
S
H
M
S
L
D
D
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.2
65
N.A.
77.2
72
N.A.
61.9
29.6
N.A.
45.9
44
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
96.8
70.7
N.A.
85
78.8
N.A.
75.2
48.2
N.A.
61.6
60.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
13.3
13.3
N.A.
13.3
6.6
N.A.
53.3
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
20
20
N.A.
26.6
26.6
N.A.
60
13.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
50
0
0
0
0
0
10
0
0
30
% A
% Cys:
0
0
0
0
0
0
0
0
0
40
0
0
0
0
0
% C
% Asp:
0
0
0
40
0
0
0
0
10
0
0
10
50
10
10
% D
% Glu:
0
0
20
10
0
0
60
10
0
0
20
40
10
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
10
0
0
0
0
10
10
% F
% Gly:
0
0
0
10
50
10
20
0
0
0
10
0
20
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
10
10
0
10
0
50
0
% I
% Lys:
0
0
0
0
10
10
0
0
0
0
10
0
10
0
0
% K
% Leu:
0
20
0
0
0
20
10
30
40
0
50
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
20
10
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
10
10
0
0
0
0
0
% R
% Ser:
60
0
10
0
0
0
0
0
10
10
0
10
0
0
0
% S
% Thr:
0
70
10
10
10
10
0
40
0
20
0
0
0
20
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
20
10
50
0
10
0
0
0
0
0
0
0
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _