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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EML4
All Species:
4.55
Human Site:
S134
Identified Species:
10
UniProt:
Q9HC35
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HC35
NP_001138548.1
981
108903
S134
E
K
K
E
E
S
H
S
N
D
Q
S
P
Q
I
Chimpanzee
Pan troglodytes
XP_001157076
821
90327
Rhesus Macaque
Macaca mulatta
XP_001103795
821
90266
Dog
Lupus familis
XP_851484
981
109074
S134
E
K
K
E
E
S
H
S
N
D
Q
S
P
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMY5
988
110008
P145
S
P
Q
I
R
A
S
P
S
P
Q
P
S
S
Q
Rat
Rattus norvegicus
Q4V8C3
814
89783
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512831
860
95042
W44
V
K
P
C
I
E
F
W
E
K
Y
A
D
D
S
Chicken
Gallus gallus
XP_001233827
930
103014
K115
L
S
T
A
K
S
I
K
R
S
L
T
A
E
K
Frog
Xenopus laevis
Q2TAF3
927
102313
V112
L
S
S
A
A
K
S
V
K
R
S
S
T
L
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45487
891
98353
Q76
R
L
Q
N
L
E
I
Q
D
Q
S
R
S
P
T
Sea Urchin
Strong. purpuratus
Q26613
686
75435
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.2
47.2
93.1
N.A.
87.8
44.1
N.A.
42.5
79
75.9
N.A.
N.A.
N.A.
N.A.
26.1
37.5
Protein Similarity:
100
62
62.2
95.8
N.A.
92.4
59.4
N.A.
57.7
86
83.7
N.A.
N.A.
N.A.
N.A.
45.9
51.3
P-Site Identity:
100
0
0
100
N.A.
6.6
0
N.A.
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
0
0
100
N.A.
26.6
0
N.A.
13.3
26.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
10
10
0
0
0
0
0
10
10
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
19
0
0
10
10
0
% D
% Glu:
19
0
0
19
19
19
0
0
10
0
0
0
0
10
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
10
0
19
0
0
0
0
0
0
0
19
% I
% Lys:
0
28
19
0
10
10
0
10
10
10
0
0
0
0
10
% K
% Leu:
19
10
0
0
10
0
0
0
0
0
10
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
19
0
0
0
0
0
0
% N
% Pro:
0
10
10
0
0
0
0
10
0
10
0
10
19
10
0
% P
% Gln:
0
0
19
0
0
0
0
10
0
10
28
0
0
19
10
% Q
% Arg:
10
0
0
0
10
0
0
0
10
10
0
10
0
0
0
% R
% Ser:
10
19
10
0
0
28
19
19
10
10
19
28
19
10
10
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
10
10
0
10
% T
% Val:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _