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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EML4
All Species:
5.45
Human Site:
T486
Identified Species:
12
UniProt:
Q9HC35
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HC35
NP_001138548.1
981
108903
T486
M
L
I
W
S
K
T
T
V
E
P
T
P
G
K
Chimpanzee
Pan troglodytes
XP_001157076
821
90327
G345
A
F
S
K
S
N
G
G
T
N
L
C
A
V
D
Rhesus Macaque
Macaca mulatta
XP_001103795
821
90266
G345
A
F
S
K
S
N
G
G
T
N
L
C
A
V
D
Dog
Lupus familis
XP_851484
981
109074
T486
I
L
I
W
S
K
T
T
V
E
P
T
P
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMY5
988
110008
M497
M
L
I
W
S
K
T
M
V
E
P
P
P
G
K
Rat
Rattus norvegicus
Q4V8C3
814
89783
G338
A
F
S
K
S
N
G
G
S
H
L
C
A
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512831
860
95042
G383
I
A
F
S
K
S
N
G
G
S
N
L
C
S
V
Chicken
Gallus gallus
XP_001233827
930
103014
I454
G
P
K
G
V
Y
Q
I
S
R
Q
I
K
A
H
Frog
Xenopus laevis
Q2TAF3
927
102313
D451
S
K
Q
I
K
A
H
D
G
S
V
F
T
L
C
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45487
891
98353
S415
G
I
C
H
V
A
F
S
K
T
D
S
G
S
L
Sea Urchin
Strong. purpuratus
Q26613
686
75435
G210
S
F
S
K
V
N
V
G
V
H
L
A
A
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.2
47.2
93.1
N.A.
87.8
44.1
N.A.
42.5
79
75.9
N.A.
N.A.
N.A.
N.A.
26.1
37.5
Protein Similarity:
100
62
62.2
95.8
N.A.
92.4
59.4
N.A.
57.7
86
83.7
N.A.
N.A.
N.A.
N.A.
45.9
51.3
P-Site Identity:
100
6.6
6.6
93.3
N.A.
86.6
6.6
N.A.
0
0
0
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
6.6
6.6
100
N.A.
86.6
6.6
N.A.
6.6
0
0
N.A.
N.A.
N.A.
N.A.
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
10
0
0
0
19
0
0
0
0
0
10
37
10
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
28
10
0
10
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
37
% D
% Glu:
0
0
0
0
0
0
0
0
0
28
0
0
0
0
0
% E
% Phe:
0
37
10
0
0
0
10
0
0
0
0
10
0
0
0
% F
% Gly:
19
0
0
10
0
0
28
46
19
0
0
0
10
28
0
% G
% His:
0
0
0
10
0
0
10
0
0
19
0
0
0
0
10
% H
% Ile:
19
10
28
10
0
0
0
10
0
0
0
10
0
0
0
% I
% Lys:
0
10
10
37
19
28
0
0
10
0
0
0
10
0
28
% K
% Leu:
0
28
0
0
0
0
0
0
0
0
37
10
0
10
10
% L
% Met:
19
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
37
10
0
0
19
10
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
28
10
28
0
0
% P
% Gln:
0
0
10
0
0
0
10
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
19
0
37
10
55
10
0
10
19
19
0
10
0
19
0
% S
% Thr:
0
0
0
0
0
0
28
19
19
10
0
19
10
0
0
% T
% Val:
0
0
0
0
28
0
10
0
37
0
10
0
0
37
10
% V
% Trp:
0
0
0
28
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _