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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EML4
All Species:
16.67
Human Site:
T838
Identified Species:
36.67
UniProt:
Q9HC35
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HC35
NP_001138548.1
981
108903
T838
S
A
H
S
S
H
V
T
N
V
S
F
T
H
N
Chimpanzee
Pan troglodytes
XP_001157076
821
90327
S679
G
K
C
S
G
H
S
S
F
I
T
H
L
D
W
Rhesus Macaque
Macaca mulatta
XP_001103795
821
90266
S679
G
K
C
S
G
H
S
S
F
I
T
H
L
D
W
Dog
Lupus familis
XP_851484
981
109074
T838
S
A
H
S
S
H
V
T
N
V
S
F
T
H
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMY5
988
110008
S845
S
H
K
Y
S
A
H
S
S
H
V
T
N
V
S
Rat
Rattus norvegicus
Q4V8C3
814
89783
S672
G
K
C
S
G
H
S
S
F
I
T
H
L
D
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512831
860
95042
S717
I
G
K
C
S
G
H
S
S
F
I
T
H
L
D
Chicken
Gallus gallus
XP_001233827
930
103014
S788
H
K
Y
S
A
H
S
S
H
V
T
N
V
S
F
Frog
Xenopus laevis
Q2TAF3
927
102313
T785
H
V
T
N
V
S
F
T
H
N
D
G
H
L
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45487
891
98353
A749
S
K
N
L
L
V
I
A
R
I
H
H
I
P
A
Sea Urchin
Strong. purpuratus
Q26613
686
75435
S544
G
K
C
S
G
H
S
S
F
V
T
H
I
D
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.2
47.2
93.1
N.A.
87.8
44.1
N.A.
42.5
79
75.9
N.A.
N.A.
N.A.
N.A.
26.1
37.5
Protein Similarity:
100
62
62.2
95.8
N.A.
92.4
59.4
N.A.
57.7
86
83.7
N.A.
N.A.
N.A.
N.A.
45.9
51.3
P-Site Identity:
100
13.3
13.3
100
N.A.
13.3
13.3
N.A.
6.6
20
6.6
N.A.
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
100
33.3
33.3
100
N.A.
33.3
33.3
N.A.
26.6
53.3
20
N.A.
N.A.
N.A.
N.A.
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
10
10
0
10
0
0
0
0
0
0
10
% A
% Cys:
0
0
37
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
37
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
37
10
0
19
0
0
10
% F
% Gly:
37
10
0
0
37
10
0
0
0
0
0
10
0
0
0
% G
% His:
19
10
19
0
0
64
19
0
19
10
10
46
19
19
0
% H
% Ile:
10
0
0
0
0
0
10
0
0
37
10
0
19
0
10
% I
% Lys:
0
55
19
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
10
0
0
0
0
0
0
0
28
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
0
19
10
0
10
10
0
19
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
37
0
0
64
37
10
46
64
19
0
19
0
0
10
10
% S
% Thr:
0
0
10
0
0
0
0
28
0
0
46
19
19
0
0
% T
% Val:
0
10
0
0
10
10
19
0
0
37
10
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
37
% W
% Tyr:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _