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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EML4
All Species:
8.79
Human Site:
Y747
Identified Species:
19.33
UniProt:
Q9HC35
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HC35
NP_001138548.1
981
108903
Y747
S
G
D
Y
E
I
L
Y
W
D
I
P
N
G
C
Chimpanzee
Pan troglodytes
XP_001157076
821
90327
A593
D
K
I
I
E
D
P
A
Q
S
S
G
F
H
P
Rhesus Macaque
Macaca mulatta
XP_001103795
821
90266
A593
D
K
I
I
E
D
P
A
Q
S
S
G
F
H
P
Dog
Lupus familis
XP_851484
981
109074
Y747
S
G
D
Y
E
I
L
Y
W
D
I
P
S
G
C
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMY5
988
110008
Y758
S
G
D
Y
E
I
L
Y
W
D
I
E
N
G
C
Rat
Rattus norvegicus
Q4V8C3
814
89783
A586
D
K
I
I
E
D
P
A
Q
S
S
G
F
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512831
860
95042
P631
W
N
K
I
I
E
D
P
A
Q
A
S
G
F
H
Chicken
Gallus gallus
XP_001233827
930
103014
D702
D
Y
E
I
L
Y
W
D
I
P
S
G
C
K
L
Frog
Xenopus laevis
Q2TAF3
927
102313
I699
I
P
S
G
C
K
L
I
R
N
R
S
E
C
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45487
891
98353
F663
H
I
D
K
K
V
E
F
S
K
K
F
I
D
S
Sea Urchin
Strong. purpuratus
Q26613
686
75435
C458
N
K
L
M
E
D
G
C
Q
S
A
G
F
H
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.2
47.2
93.1
N.A.
87.8
44.1
N.A.
42.5
79
75.9
N.A.
N.A.
N.A.
N.A.
26.1
37.5
Protein Similarity:
100
62
62.2
95.8
N.A.
92.4
59.4
N.A.
57.7
86
83.7
N.A.
N.A.
N.A.
N.A.
45.9
51.3
P-Site Identity:
100
6.6
6.6
93.3
N.A.
93.3
6.6
N.A.
0
0
6.6
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
6.6
6.6
100
N.A.
93.3
6.6
N.A.
0
6.6
13.3
N.A.
N.A.
N.A.
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
28
10
0
19
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
10
0
0
0
0
10
10
28
% C
% Asp:
37
0
37
0
0
37
10
10
0
28
0
0
0
10
0
% D
% Glu:
0
0
10
0
64
10
10
0
0
0
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
10
37
10
0
% F
% Gly:
0
28
0
10
0
0
10
0
0
0
0
46
10
28
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
37
10
% H
% Ile:
10
10
28
46
10
28
0
10
10
0
28
0
10
0
0
% I
% Lys:
0
37
10
10
10
10
0
0
0
10
10
0
0
10
10
% K
% Leu:
0
0
10
0
10
0
37
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
0
0
0
0
0
10
0
0
19
0
0
% N
% Pro:
0
10
0
0
0
0
28
10
0
10
0
19
0
0
37
% P
% Gln:
0
0
0
0
0
0
0
0
37
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% R
% Ser:
28
0
10
0
0
0
0
0
10
37
37
19
10
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
10
0
28
0
0
0
0
0
0
% W
% Tyr:
0
10
0
28
0
10
0
28
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _