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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLOD4
All Species:
34.24
Human Site:
S280
Identified Species:
75.33
UniProt:
Q9HC38
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HC38
NP_057164.3
313
34793
S280
D
E
A
F
R
E
L
S
K
M
D
P
E
G
S
Chimpanzee
Pan troglodytes
XP_001152739
313
34827
S280
D
E
A
F
R
E
L
S
K
M
D
P
E
G
S
Rhesus Macaque
Macaca mulatta
XP_001084753
298
33234
S265
D
E
A
F
R
E
L
S
K
V
D
P
E
G
S
Dog
Lupus familis
XP_868387
312
35223
S279
D
E
A
F
R
E
L
S
K
M
D
P
E
G
S
Cat
Felis silvestris
Mouse
Mus musculus
NP_080305
298
33298
S265
D
E
A
F
R
E
L
S
K
M
D
P
K
G
S
Rat
Rattus norvegicus
NP_001014249
298
33249
S265
D
E
A
F
R
E
L
S
K
M
D
P
K
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506927
300
33293
S267
D
E
A
F
R
E
L
S
R
V
D
P
G
G
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085671
298
33374
S265
D
E
A
F
R
E
L
S
Q
T
D
P
T
A
D
Zebra Danio
Brachydanio rerio
NP_001004613
298
33014
S265
D
E
A
F
R
Q
L
S
A
V
D
P
N
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608420
288
31624
F256
P
D
G
H
E
I
C
F
V
D
E
E
G
F
G
Honey Bee
Apis mellifera
XP_625100
281
32109
H249
I
L
A
D
P
D
G
H
E
I
C
F
V
D
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
89.1
86.5
N.A.
83
82.1
N.A.
73.8
N.A.
67.7
67
N.A.
45
45.6
N.A.
N.A.
Protein Similarity:
100
99.6
91.3
92
N.A.
87.8
88.1
N.A.
85.3
N.A.
80.5
83
N.A.
61.9
64.8
N.A.
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
80
N.A.
66.6
66.6
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
N.A.
73.3
86.6
N.A.
13.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
91
0
0
0
0
0
10
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% C
% Asp:
82
10
0
10
0
10
0
0
0
10
82
0
0
10
19
% D
% Glu:
0
82
0
0
10
73
0
0
10
0
10
10
37
0
0
% E
% Phe:
0
0
0
82
0
0
0
10
0
0
0
10
0
10
0
% F
% Gly:
0
0
10
0
0
0
10
0
0
0
0
0
19
73
10
% G
% His:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
55
0
0
0
19
0
0
% K
% Leu:
0
10
0
0
0
0
82
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
46
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% N
% Pro:
10
0
0
0
10
0
0
0
0
0
0
82
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
82
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
64
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
28
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _