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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC24A3 All Species: 19.39
Human Site: S336 Identified Species: 35.56
UniProt: Q9HC58 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HC58 NP_065740.2 644 71992 S336 G L R I M I T S H F P P K T R
Chimpanzee Pan troglodytes XP_522932 563 62599 R278 I T N K F G P R T R L R M A S
Rhesus Macaque Macaca mulatta XP_001090485 1031 115000 S723 G L R I M I T S H F P P K T R
Dog Lupus familis XP_849585 699 77549 S388 G L R I M I T S H F P P K T R
Cat Felis silvestris
Mouse Mus musculus Q99PD7 645 71896 S335 G L R I M I T S H F P P K T R
Rat Rattus norvegicus Q9EPQ0 624 69371 S317 G L R I M I T S H F P P K T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514620 619 69603 S316 V D E I L C S S P P K F S F P
Chicken Gallus gallus Q9IAL7 651 72677 L359 M I H T L D P L A E E L G S Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q49SH1 513 56764 F228 V Y V A V L C F D L R I S E Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U6A0 888 95868 L596 V E L P Q C V L H K S S Q M P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34322 672 74805 R320 E K A Q T T R R Y T K R A S F
Sea Urchin Strong. purpuratus XP_780438 570 63240 D285 P K R L T F S D A G L R L M L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LJI2 643 70138 E330 P M N T P L I E T E T E D G P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.6 61.7 80.9 N.A. 96.4 93.9 N.A. 59.6 35.3 N.A. 36.4 N.A. 28.9 N.A. 22.3 47.3
Protein Similarity: 100 68.6 62 85.5 N.A. 97.8 95.5 N.A. 73.4 55.6 N.A. 53.5 N.A. 44 N.A. 43.5 61.8
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 13.3 0 N.A. 0 N.A. 6.6 N.A. 0 6.6
P-Site Similarity: 100 0 100 100 N.A. 100 100 N.A. 26.6 20 N.A. 13.3 N.A. 13.3 N.A. 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. 21.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 41.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 0 0 0 16 0 0 0 8 8 0 % A
% Cys: 0 0 0 0 0 16 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 8 0 8 8 0 0 0 8 0 0 % D
% Glu: 8 8 8 0 0 0 0 8 0 16 8 8 0 8 0 % E
% Phe: 0 0 0 0 8 8 0 8 0 39 0 8 0 8 8 % F
% Gly: 39 0 0 0 0 8 0 0 0 8 0 0 8 8 0 % G
% His: 0 0 8 0 0 0 0 0 47 0 0 0 0 0 0 % H
% Ile: 8 8 0 47 0 39 8 0 0 0 0 8 0 0 0 % I
% Lys: 0 16 0 8 0 0 0 0 0 8 16 0 39 0 0 % K
% Leu: 0 39 8 8 16 16 0 16 0 8 16 8 8 0 8 % L
% Met: 8 8 0 0 39 0 0 0 0 0 0 0 8 16 0 % M
% Asn: 0 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 16 0 0 8 8 0 16 0 8 8 39 39 0 0 24 % P
% Gln: 0 0 0 8 8 0 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 47 0 0 0 8 16 0 8 8 24 0 0 39 % R
% Ser: 0 0 0 0 0 0 16 47 0 0 8 8 16 16 8 % S
% Thr: 0 8 0 16 16 8 39 0 16 8 8 0 0 39 0 % T
% Val: 24 0 8 0 8 0 8 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _