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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC24A3
All Species:
21.82
Human Site:
T436
Identified Species:
40
UniProt:
Q9HC58
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HC58
NP_065740.2
644
71992
T436
D
D
D
E
G
P
Y
T
P
F
D
T
P
S
G
Chimpanzee
Pan troglodytes
XP_522932
563
62599
M369
R
G
D
K
V
K
W
M
F
T
W
P
L
I
F
Rhesus Macaque
Macaca mulatta
XP_001090485
1031
115000
T823
D
D
D
E
G
P
Y
T
P
F
D
P
P
S
G
Dog
Lupus familis
XP_849585
699
77549
T491
D
D
D
E
G
P
Y
T
P
F
D
L
P
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q99PD7
645
71896
T438
D
D
D
E
G
P
Y
T
P
F
D
P
P
S
G
Rat
Rattus norvegicus
Q9EPQ0
624
69371
T417
D
D
D
E
G
P
Y
T
P
F
D
P
P
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514620
619
69603
S410
V
P
E
N
T
F
L
S
P
F
S
M
P
E
A
Chicken
Gallus gallus
Q9IAL7
651
72677
S450
E
D
E
D
Q
P
L
S
L
A
W
P
D
T
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q49SH1
513
56764
I319
P
D
H
D
L
K
R
I
L
W
V
L
S
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U6A0
888
95868
L689
I
E
D
E
P
E
P
L
S
M
A
W
P
D
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34322
672
74805
V431
V
M
A
Y
I
N
V
V
P
N
L
L
F
K
L
Sea Urchin
Strong. purpuratus
XP_780438
570
63240
K376
S
G
I
I
N
I
L
K
W
I
V
T
L
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LJI2
643
70138
S434
V
L
L
A
S
L
W
S
S
Q
D
D
V
S
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.6
61.7
80.9
N.A.
96.4
93.9
N.A.
59.6
35.3
N.A.
36.4
N.A.
28.9
N.A.
22.3
47.3
Protein Similarity:
100
68.6
62
85.5
N.A.
97.8
95.5
N.A.
73.4
55.6
N.A.
53.5
N.A.
44
N.A.
43.5
61.8
P-Site Identity:
100
6.6
93.3
93.3
N.A.
93.3
93.3
N.A.
20
13.3
N.A.
6.6
N.A.
20
N.A.
6.6
6.6
P-Site Similarity:
100
20
93.3
93.3
N.A.
93.3
93.3
N.A.
33.3
46.6
N.A.
20
N.A.
26.6
N.A.
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
0
0
8
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
39
54
54
16
0
0
0
0
0
0
47
8
8
8
0
% D
% Glu:
8
8
16
47
0
8
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
8
0
0
8
47
0
0
8
0
8
% F
% Gly:
0
16
0
0
39
0
0
0
0
0
0
0
0
0
39
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
8
8
8
0
8
0
8
0
0
0
8
8
% I
% Lys:
0
0
0
8
0
16
0
8
0
0
0
0
0
8
0
% K
% Leu:
0
8
8
0
8
8
24
8
16
0
8
24
16
8
16
% L
% Met:
0
8
0
0
0
0
0
8
0
8
0
8
0
0
0
% M
% Asn:
0
0
0
8
8
8
0
0
0
8
0
0
0
0
0
% N
% Pro:
8
8
0
0
8
47
8
0
54
0
0
39
54
8
16
% P
% Gln:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
8
0
0
24
16
0
8
0
8
47
0
% S
% Thr:
0
0
0
0
8
0
0
39
0
8
0
16
0
8
8
% T
% Val:
24
0
0
0
8
0
8
8
0
0
16
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
16
0
8
8
16
8
0
0
0
% W
% Tyr:
0
0
0
8
0
0
39
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _