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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPJ
All Species:
15.76
Human Site:
S442
Identified Species:
34.67
UniProt:
Q9HC77
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HC77
NP_060921.3
1338
153000
S442
N
P
I
L
K
K
D
S
K
A
R
T
K
S
G
Chimpanzee
Pan troglodytes
Q5BQN8
1338
152866
S443
N
P
I
L
K
K
D
S
K
A
R
T
K
S
G
Rhesus Macaque
Macaca mulatta
XP_001117666
1300
147285
S407
N
P
A
L
K
K
E
S
K
A
G
T
K
S
G
Dog
Lupus familis
XP_543181
1355
154131
N444
N
P
P
I
K
K
S
N
K
G
R
A
K
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q569L8
1344
153034
S430
T
P
T
V
K
K
D
S
K
A
R
P
K
A
G
Rat
Rattus norvegicus
NP_001100735
1307
147827
S391
T
T
S
V
K
K
D
S
K
A
R
S
K
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510637
1256
142839
K365
G
S
G
L
L
T
Q
K
A
R
V
L
R
T
I
Chicken
Gallus gallus
XP_417152
1227
138809
Q357
K
T
L
V
L
R
N
Q
N
G
K
N
S
L
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697409
1124
126471
G306
N
S
I
N
K
S
E
G
S
K
S
T
H
P
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649701
901
103264
Q83
W
D
E
E
H
S
I
Q
M
P
R
L
A
A
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201804
443
50264
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
86.6
78.7
N.A.
73.5
69.5
N.A.
53
47.5
N.A.
34
N.A.
22.5
N.A.
N.A.
20.7
Protein Similarity:
100
99.1
90.2
86.4
N.A.
82.6
79.1
N.A.
65.9
61.8
N.A.
50.5
N.A.
39
N.A.
N.A.
27.7
P-Site Identity:
100
100
80
60
N.A.
66.6
60
N.A.
6.6
0
N.A.
26.6
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
73.3
N.A.
80
80
N.A.
20
33.3
N.A.
33.3
N.A.
13.3
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
10
46
0
10
10
28
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
37
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
10
10
0
0
19
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
0
0
0
10
0
19
10
0
0
0
55
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
28
10
0
0
10
0
0
0
0
0
0
0
10
% I
% Lys:
10
0
0
0
64
55
0
10
55
10
10
0
55
0
0
% K
% Leu:
0
0
10
37
19
0
0
0
0
0
0
19
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% M
% Asn:
46
0
0
10
0
0
10
10
10
0
0
10
0
0
0
% N
% Pro:
0
46
10
0
0
0
0
0
0
10
0
10
0
10
10
% P
% Gln:
0
0
0
0
0
0
10
19
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
10
55
0
10
0
0
% R
% Ser:
0
19
10
0
0
19
10
46
10
0
10
10
10
37
0
% S
% Thr:
19
19
10
0
0
10
0
0
0
0
0
37
0
10
0
% T
% Val:
0
0
0
28
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _