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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CENPJ All Species: 8.79
Human Site: S879 Identified Species: 19.33
UniProt: Q9HC77 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HC77 NP_060921.3 1338 153000 S879 S L K P K P K S D S H L G N E
Chimpanzee Pan troglodytes Q5BQN8 1338 152866 S880 S L K P K P K S D S H L G N E
Rhesus Macaque Macaca mulatta XP_001117666 1300 147285 S846 A L K P K P K S D S H L G T E
Dog Lupus familis XP_543181 1355 154131 A887 A L K L K P K A G S H L G N E
Cat Felis silvestris
Mouse Mus musculus Q569L8 1344 153034 L871 S L K P K P K L D S H L E N E
Rat Rattus norvegicus NP_001100735 1307 147827 L830 S L K P K P K L D S H V E N E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510637 1256 142839 K792 P S L K P K K K P G S S P G R
Chicken Gallus gallus XP_417152 1227 138809 Q774 F P S L K T K Q K T G C H P E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_697409 1124 126471 K719 R E N L K K D K A D F E K K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649701 901 103264 L496 K I Q A E I Y L H D E R M K I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001201804 443 50264 R37 E T E N T E L R E E V R L M E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 86.6 78.7 N.A. 73.5 69.5 N.A. 53 47.5 N.A. 34 N.A. 22.5 N.A. N.A. 20.7
Protein Similarity: 100 99.1 90.2 86.4 N.A. 82.6 79.1 N.A. 65.9 61.8 N.A. 50.5 N.A. 39 N.A. N.A. 27.7
P-Site Identity: 100 100 86.6 73.3 N.A. 86.6 80 N.A. 6.6 20 N.A. 6.6 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. 6.6 26.6 N.A. 6.6 N.A. 20 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 0 10 0 0 0 10 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 46 19 0 0 0 0 0 % D
% Glu: 10 10 10 0 10 10 0 0 10 10 10 10 19 0 73 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 10 10 0 37 10 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 55 0 10 0 0 % H
% Ile: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 10 % I
% Lys: 10 0 55 10 73 19 73 19 10 0 0 0 10 19 0 % K
% Leu: 0 55 10 28 0 0 10 28 0 0 0 46 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % M
% Asn: 0 0 10 10 0 0 0 0 0 0 0 0 0 46 0 % N
% Pro: 10 10 0 46 10 55 0 0 10 0 0 0 10 10 0 % P
% Gln: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 10 0 0 0 19 0 0 19 % R
% Ser: 37 10 10 0 0 0 0 28 0 55 10 10 0 0 0 % S
% Thr: 0 10 0 0 10 10 0 0 0 10 0 0 0 10 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _