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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK6
All Species:
27.88
Human Site:
Y298
Identified Species:
68.15
UniProt:
Q9HC98
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HC98
NP_001138473.1
313
35714
Y298
H
Q
R
P
D
I
G
Y
V
H
Q
V
A
K
Q
Chimpanzee
Pan troglodytes
XP_001138236
432
48499
Y417
D
Q
R
P
D
I
G
Y
V
H
Q
V
A
K
Q
Rhesus Macaque
Macaca mulatta
XP_001110532
302
34516
Y287
E
K
R
P
D
V
A
Y
V
Y
D
V
A
K
R
Dog
Lupus familis
XP_851372
313
35673
Y298
N
Q
R
P
D
I
G
Y
V
H
Q
V
A
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES70
313
35724
Y298
D
H
R
P
D
I
V
Y
V
H
Q
V
A
R
Q
Rat
Rattus norvegicus
P59895
313
35817
Y298
N
H
R
P
D
I
E
Y
V
H
Q
V
A
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509791
504
55648
G488
P
D
Q
R
P
D
I
G
Y
V
H
Q
T
A
K
Chicken
Gallus gallus
NP_001012549
314
36302
Y299
D
Q
R
P
D
I
G
Y
V
H
Q
I
A
K
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510080
302
34559
E276
S
K
R
P
E
T
S
E
V
L
Q
V
A
E
H
Sea Urchin
Strong. purpuratus
XP_781870
294
33867
Y278
N
L
R
P
D
V
S
Y
V
L
E
V
A
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.7
76.6
96.8
N.A.
95.2
96.1
N.A.
53.7
88.5
N.A.
N.A.
N.A.
N.A.
N.A.
65.1
70.9
Protein Similarity:
100
71.9
85.6
97.4
N.A.
96.4
97.4
N.A.
56.9
91.4
N.A.
N.A.
N.A.
N.A.
N.A.
77.9
83
P-Site Identity:
100
93.3
53.3
93.3
N.A.
73.3
80
N.A.
0
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
40
53.3
P-Site Similarity:
100
93.3
80
100
N.A.
80
86.6
N.A.
13.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
60
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
90
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
30
10
0
0
80
10
0
0
0
0
10
0
0
0
0
% D
% Glu:
10
0
0
0
10
0
10
10
0
0
10
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
40
10
0
0
0
0
0
0
0
% G
% His:
10
20
0
0
0
0
0
0
0
60
10
0
0
0
10
% H
% Ile:
0
0
0
0
0
60
10
0
0
0
0
10
0
0
0
% I
% Lys:
0
20
0
0
0
0
0
0
0
0
0
0
0
70
10
% K
% Leu:
0
10
0
0
0
0
0
0
0
20
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
30
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
90
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
40
10
0
0
0
0
0
0
0
70
10
0
0
60
% Q
% Arg:
0
0
90
10
0
0
0
0
0
0
0
0
0
10
20
% R
% Ser:
10
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
20
10
0
90
10
0
80
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
10
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _