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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE28
All Species:
18.18
Human Site:
S254
Identified Species:
36.36
UniProt:
Q9HCC9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCC9
NP_066023.1
887
96490
S254
D
R
K
V
E
D
M
S
E
L
F
R
P
F
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116192
715
75453
L109
L
L
R
K
I
R
D
L
L
Q
T
L
T
E
E
Dog
Lupus familis
XP_545920
606
64606
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPK7
905
99769
S254
D
R
K
V
E
D
M
S
E
L
F
R
P
F
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521608
312
34972
Chicken
Gallus gallus
XP_420832
912
101903
S265
D
H
K
P
E
D
M
S
E
L
F
R
P
F
H
Frog
Xenopus laevis
NP_001087164
538
61276
Zebra Danio
Brachydanio rerio
A0JMD2
969
106945
S254
D
R
K
P
E
D
M
S
E
L
F
R
P
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB70
989
108781
S265
D
M
P
G
D
Q
L
S
E
M
F
R
P
F
R
Honey Bee
Apis mellifera
XP_397433
1240
139257
E254
N
S
P
D
N
I
S
E
V
F
R
P
F
R
S
Nematode Worm
Caenorhab. elegans
Q9TZD0
661
74507
L55
C
N
A
L
V
T
R
L
R
V
A
Q
D
R
V
Sea Urchin
Strong. purpuratus
XP_785516
997
110048
S253
A
K
P
A
S
Q
I
S
E
L
F
R
P
F
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
57.9
45.4
N.A.
81.7
N.A.
N.A.
30.5
69.1
32.1
55.1
N.A.
31
32.1
30.4
36.7
Protein Similarity:
100
N.A.
62.9
51
N.A.
86.5
N.A.
N.A.
32.8
78.9
43.6
64.4
N.A.
44.9
45
44
50.7
P-Site Identity:
100
N.A.
0
0
N.A.
100
N.A.
N.A.
0
86.6
0
86.6
N.A.
46.6
0
0
46.6
P-Site Similarity:
100
N.A.
6.6
0
N.A.
100
N.A.
N.A.
0
86.6
0
86.6
N.A.
66.6
6.6
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
9
0
0
0
0
0
0
9
0
0
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
42
0
0
9
9
34
9
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
34
0
0
9
50
0
0
0
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
50
0
9
50
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
25
% H
% Ile:
0
0
0
0
9
9
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
34
9
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
9
0
9
0
0
9
17
9
42
0
9
0
0
0
% L
% Met:
0
9
0
0
0
0
34
0
0
9
0
0
0
0
0
% M
% Asn:
9
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
25
17
0
0
0
0
0
0
0
9
50
0
0
% P
% Gln:
0
0
0
0
0
17
0
0
0
9
0
9
0
0
9
% Q
% Arg:
0
25
9
0
0
9
9
0
9
0
9
50
0
17
17
% R
% Ser:
0
9
0
0
9
0
9
50
0
0
0
0
0
0
9
% S
% Thr:
0
0
0
0
0
9
0
0
0
0
9
0
9
0
0
% T
% Val:
0
0
0
17
9
0
0
0
9
9
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _