KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE28
All Species:
12.73
Human Site:
S358
Identified Species:
25.45
UniProt:
Q9HCC9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCC9
NP_066023.1
887
96490
S358
R
A
G
D
E
M
S
S
L
L
S
P
P
I
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116192
715
75453
Q206
L
S
P
P
S
A
C
Q
S
P
A
H
R
P
G
Dog
Lupus familis
XP_545920
606
64606
N97
E
L
H
T
L
E
R
N
L
C
I
S
Q
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPK7
905
99769
S358
R
A
G
D
E
M
S
S
L
L
S
P
P
S
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521608
312
34972
Chicken
Gallus gallus
XP_420832
912
101903
S368
R
V
G
D
E
M
S
S
L
L
S
P
P
S
I
Frog
Xenopus laevis
NP_001087164
538
61276
I29
M
L
G
I
I
E
Q
I
M
E
L
C
V
P
T
Zebra Danio
Brachydanio rerio
A0JMD2
969
106945
T391
Q
V
G
D
E
M
S
T
L
L
S
P
P
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB70
989
108781
E366
T
N
T
H
R
T
V
E
R
L
V
D
Q
R
N
Honey Bee
Apis mellifera
XP_397433
1240
139257
N389
E
T
G
P
N
R
L
N
G
Y
E
E
A
V
R
Nematode Worm
Caenorhab. elegans
Q9TZD0
661
74507
S152
N
Q
S
L
R
D
P
S
A
Y
N
P
V
I
K
Sea Urchin
Strong. purpuratus
XP_785516
997
110048
G415
D
S
L
D
G
F
A
G
G
E
T
C
K
C
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
57.9
45.4
N.A.
81.7
N.A.
N.A.
30.5
69.1
32.1
55.1
N.A.
31
32.1
30.4
36.7
Protein Similarity:
100
N.A.
62.9
51
N.A.
86.5
N.A.
N.A.
32.8
78.9
43.6
64.4
N.A.
44.9
45
44
50.7
P-Site Identity:
100
N.A.
0
6.6
N.A.
93.3
N.A.
N.A.
0
80
6.6
66.6
N.A.
6.6
6.6
20
6.6
P-Site Similarity:
100
N.A.
13.3
13.3
N.A.
93.3
N.A.
N.A.
0
80
13.3
80
N.A.
6.6
20
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
0
9
9
0
9
0
9
0
9
0
17
% A
% Cys:
0
0
0
0
0
0
9
0
0
9
0
17
0
9
0
% C
% Asp:
9
0
0
42
0
9
0
0
0
0
0
9
0
9
0
% D
% Glu:
17
0
0
0
34
17
0
9
0
17
9
9
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
50
0
9
0
0
9
17
0
0
0
0
0
9
% G
% His:
0
0
9
9
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
9
9
0
0
9
0
0
9
0
0
17
17
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% K
% Leu:
9
17
9
9
9
0
9
0
42
42
9
0
0
0
0
% L
% Met:
9
0
0
0
0
34
0
0
9
0
0
0
0
0
0
% M
% Asn:
9
9
0
0
9
0
0
17
0
0
9
0
0
0
9
% N
% Pro:
0
0
9
17
0
0
9
0
0
9
0
42
34
17
0
% P
% Gln:
9
9
0
0
0
0
9
9
0
0
0
0
17
0
9
% Q
% Arg:
25
0
0
0
17
9
9
0
9
0
0
0
9
9
9
% R
% Ser:
0
17
9
0
9
0
34
34
9
0
34
9
0
25
0
% S
% Thr:
9
9
9
9
0
9
0
9
0
0
9
0
0
0
9
% T
% Val:
0
17
0
0
0
0
9
0
0
0
9
0
17
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _