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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE28
All Species:
5.76
Human Site:
S523
Identified Species:
11.52
UniProt:
Q9HCC9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCC9
NP_066023.1
887
96490
S523
T
V
I
F
N
P
K
S
P
T
S
L
D
S
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116192
715
75453
S366
F
N
P
K
S
P
T
S
L
D
S
A
V
A
T
Dog
Lupus familis
XP_545920
606
64606
D257
N
N
N
D
V
S
H
D
K
M
W
A
L
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPK7
905
99769
S525
K
S
P
T
S
Q
D
S
A
V
A
A
Q
E
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521608
312
34972
Chicken
Gallus gallus
XP_420832
912
101903
S537
K
S
P
S
S
S
E
S
P
V
T
P
E
A
A
Frog
Xenopus laevis
NP_001087164
538
61276
L189
L
M
I
S
I
P
R
L
A
I
I
S
G
L
L
Zebra Danio
Brachydanio rerio
A0JMD2
969
106945
C581
T
Q
C
L
L
N
S
C
V
C
C
A
G
G
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB70
989
108781
P554
L
P
S
S
D
N
E
P
L
A
E
P
T
T
I
Honey Bee
Apis mellifera
XP_397433
1240
139257
A662
I
E
V
H
N
L
H
A
G
S
N
A
Q
E
K
Nematode Worm
Caenorhab. elegans
Q9TZD0
661
74507
T312
S
D
F
R
T
N
A
T
D
E
E
K
A
K
N
Sea Urchin
Strong. purpuratus
XP_785516
997
110048
E603
G
K
G
K
P
S
T
E
L
N
T
T
G
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
57.9
45.4
N.A.
81.7
N.A.
N.A.
30.5
69.1
32.1
55.1
N.A.
31
32.1
30.4
36.7
Protein Similarity:
100
N.A.
62.9
51
N.A.
86.5
N.A.
N.A.
32.8
78.9
43.6
64.4
N.A.
44.9
45
44
50.7
P-Site Identity:
100
N.A.
20
0
N.A.
13.3
N.A.
N.A.
0
20
13.3
6.6
N.A.
0
6.6
0
0
P-Site Similarity:
100
N.A.
33.3
0
N.A.
26.6
N.A.
N.A.
0
53.3
26.6
6.6
N.A.
20
33.3
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
9
17
9
9
42
9
17
25
% A
% Cys:
0
0
9
0
0
0
0
9
0
9
9
0
0
0
9
% C
% Asp:
0
9
0
9
9
0
9
9
9
9
0
0
9
0
0
% D
% Glu:
0
9
0
0
0
0
17
9
0
9
17
0
9
17
0
% E
% Phe:
9
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
9
0
0
0
0
0
9
0
0
0
25
17
0
% G
% His:
0
0
0
9
0
0
17
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
17
0
9
0
0
0
0
9
9
0
0
0
9
% I
% Lys:
17
9
0
17
0
0
9
0
9
0
0
9
0
9
9
% K
% Leu:
17
0
0
9
9
9
0
9
25
0
0
9
9
9
9
% L
% Met:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
9
17
9
0
17
25
0
0
0
9
9
0
0
0
9
% N
% Pro:
0
9
25
0
9
25
0
9
17
0
0
17
0
0
9
% P
% Gln:
0
9
0
0
0
9
0
0
0
0
0
0
17
0
0
% Q
% Arg:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% R
% Ser:
9
17
9
25
25
25
9
34
0
9
17
9
0
9
0
% S
% Thr:
17
0
0
9
9
0
17
9
0
9
17
9
9
17
9
% T
% Val:
0
9
9
0
9
0
0
0
9
17
0
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _