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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE28
All Species:
2.73
Human Site:
S647
Identified Species:
5.45
UniProt:
Q9HCC9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCC9
NP_066023.1
887
96490
S647
G
S
Q
V
D
T
A
S
G
L
Q
G
E
A
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116192
715
75453
Q490
V
D
T
A
S
G
L
Q
G
E
A
G
V
A
G
Dog
Lupus familis
XP_545920
606
64606
S381
Q
D
K
C
G
P
G
S
V
I
S
A
S
Y
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPK7
905
99769
P649
C
L
A
H
T
S
G
P
Q
V
D
T
A
S
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521608
312
34972
E87
K
E
Y
Y
V
Q
Q
E
V
I
V
L
F
C
E
Chicken
Gallus gallus
XP_420832
912
101903
A661
P
V
S
S
K
C
L
A
H
S
S
G
S
Q
V
Frog
Xenopus laevis
NP_001087164
538
61276
T313
I
Q
C
Q
S
P
V
T
M
H
S
N
C
T
S
Zebra Danio
Brachydanio rerio
A0JMD2
969
106945
Q705
T
L
Q
D
T
G
C
Q
T
Q
H
N
A
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB70
989
108781
A678
H
R
L
F
V
C
I
A
G
V
A
D
Q
L
Q
Honey Bee
Apis mellifera
XP_397433
1240
139257
Q786
R
K
H
E
R
N
G
Q
K
V
Q
H
Q
E
G
Nematode Worm
Caenorhab. elegans
Q9TZD0
661
74507
V436
D
D
V
Q
A
S
D
V
L
Q
V
E
T
K
K
Sea Urchin
Strong. purpuratus
XP_785516
997
110048
S727
L
S
S
S
P
S
S
S
S
S
C
C
S
S
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
57.9
45.4
N.A.
81.7
N.A.
N.A.
30.5
69.1
32.1
55.1
N.A.
31
32.1
30.4
36.7
Protein Similarity:
100
N.A.
62.9
51
N.A.
86.5
N.A.
N.A.
32.8
78.9
43.6
64.4
N.A.
44.9
45
44
50.7
P-Site Identity:
100
N.A.
26.6
6.6
N.A.
0
N.A.
N.A.
0
6.6
0
6.6
N.A.
6.6
13.3
0
13.3
P-Site Similarity:
100
N.A.
26.6
20
N.A.
20
N.A.
N.A.
6.6
13.3
6.6
13.3
N.A.
26.6
26.6
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
9
0
9
17
0
0
17
9
17
17
0
% A
% Cys:
9
0
9
9
0
17
9
0
0
0
9
9
9
9
9
% C
% Asp:
9
25
0
9
9
0
9
0
0
0
9
9
0
0
0
% D
% Glu:
0
9
0
9
0
0
0
9
0
9
0
9
9
9
9
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
9
0
0
0
9
17
25
0
25
0
0
25
0
0
25
% G
% His:
9
0
9
9
0
0
0
0
9
9
9
9
0
0
0
% H
% Ile:
9
0
0
0
0
0
9
0
0
17
0
0
0
0
0
% I
% Lys:
9
9
9
0
9
0
0
0
9
0
0
0
0
9
9
% K
% Leu:
9
17
9
0
0
0
17
0
9
9
0
9
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
17
0
0
0
% N
% Pro:
9
0
0
0
9
17
0
9
0
0
0
0
0
0
0
% P
% Gln:
9
9
17
17
0
9
9
25
9
17
17
0
17
9
9
% Q
% Arg:
9
9
0
0
9
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
17
17
17
17
25
9
25
9
17
25
0
25
25
9
% S
% Thr:
9
0
9
0
17
9
0
9
9
0
0
9
9
9
0
% T
% Val:
9
9
9
9
17
0
9
9
17
25
17
0
9
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
9
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _