KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE28
All Species:
2.42
Human Site:
S681
Identified Species:
4.85
UniProt:
Q9HCC9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCC9
NP_066023.1
887
96490
S681
H
E
A
P
Q
A
L
S
G
S
S
S
S
T
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116192
715
75453
A516
G
S
P
S
A
H
E
A
P
Q
P
L
S
G
S
Dog
Lupus familis
XP_545920
606
64606
P407
K
G
Q
E
E
A
R
P
V
L
E
V
L
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPK7
905
99769
L699
A
Q
T
E
H
Q
H
L
L
G
S
S
S
T
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521608
312
34972
Y113
T
Q
D
M
I
D
D
Y
E
P
A
L
M
F
T
Chicken
Gallus gallus
XP_420832
912
101903
Q706
H
P
A
P
M
A
F
Q
W
S
S
S
L
M
T
Frog
Xenopus laevis
NP_001087164
538
61276
K339
Y
R
D
Q
G
V
I
K
T
A
V
F
E
C
S
Zebra Danio
Brachydanio rerio
A0JMD2
969
106945
S764
L
S
S
S
Y
A
P
S
P
V
S
S
L
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB70
989
108781
D754
E
E
V
N
P
E
L
D
N
V
F
S
A
G
G
Honey Bee
Apis mellifera
XP_397433
1240
139257
C1013
S
S
S
S
C
S
S
C
C
D
S
S
S
E
T
Nematode Worm
Caenorhab. elegans
Q9TZD0
661
74507
I462
F
D
K
S
V
K
T
I
I
P
M
Q
T
D
P
Sea Urchin
Strong. purpuratus
XP_785516
997
110048
E753
R
D
T
D
Y
K
W
E
S
D
D
S
S
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
57.9
45.4
N.A.
81.7
N.A.
N.A.
30.5
69.1
32.1
55.1
N.A.
31
32.1
30.4
36.7
Protein Similarity:
100
N.A.
62.9
51
N.A.
86.5
N.A.
N.A.
32.8
78.9
43.6
64.4
N.A.
44.9
45
44
50.7
P-Site Identity:
100
N.A.
6.6
6.6
N.A.
26.6
N.A.
N.A.
0
46.6
0
33.3
N.A.
20
20
0
13.3
P-Site Similarity:
100
N.A.
20
20
N.A.
33.3
N.A.
N.A.
13.3
46.6
26.6
40
N.A.
26.6
33.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
17
0
9
34
0
9
0
9
9
0
9
0
9
% A
% Cys:
0
0
0
0
9
0
0
9
9
0
0
0
0
9
0
% C
% Asp:
0
17
17
9
0
9
9
9
0
17
9
0
0
17
0
% D
% Glu:
9
17
0
17
9
9
9
9
9
0
9
0
9
9
0
% E
% Phe:
9
0
0
0
0
0
9
0
0
0
9
9
0
9
0
% F
% Gly:
9
9
0
0
9
0
0
0
9
9
0
0
0
17
9
% G
% His:
17
0
0
0
9
9
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
9
9
9
0
0
0
0
0
0
% I
% Lys:
9
0
9
0
0
17
0
9
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
0
0
17
9
9
9
0
17
25
0
0
% L
% Met:
0
0
0
9
9
0
0
0
0
0
9
0
9
9
0
% M
% Asn:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
9
9
17
9
0
9
9
17
17
9
0
0
9
9
% P
% Gln:
0
17
9
9
9
9
0
9
0
9
0
9
0
0
0
% Q
% Arg:
9
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% R
% Ser:
9
25
17
34
0
9
9
17
9
17
42
59
42
0
25
% S
% Thr:
9
0
17
0
0
0
9
0
9
0
0
0
9
25
42
% T
% Val:
0
0
9
0
9
9
0
0
9
17
9
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
17
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _