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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZFYVE28 All Species: 15.45
Human Site: S718 Identified Species: 30.91
UniProt: Q9HCC9 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCC9 NP_066023.1 887 96490 S718 A T R E K I R S R F H G S H D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001116192 715 75453 V553 V R A T M N S V A Q T A S P L
Dog Lupus familis XP_545920 606 64606 G444 K S P A A G S G T N P A G Q Q
Cat Felis silvestris
Mouse Mus musculus Q6ZPK7 905 99769 S736 A T R E K I R S R F H G S H D
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521608 312 34972 L150 K P E D M S E L F R P F H T L
Chicken Gallus gallus XP_420832 912 101903 S743 A T R E K I R S R F H G S N D
Frog Xenopus laevis NP_001087164 538 61276 R376 N L T F Q H V R S R Y R S D S
Zebra Danio Brachydanio rerio A0JMD2 969 106945 S801 A A H N K I R S R F H S S S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VB70 989 108781 G791 L A S Q P G E G S P S G A T T
Honey Bee Apis mellifera XP_397433 1240 139257 A1050 A N N Y K I R A K F R S S E D
Nematode Worm Caenorhab. elegans Q9TZD0 661 74507 V499 L F V C I A G V A D Q L Q T N
Sea Urchin Strong. purpuratus XP_785516 997 110048 S790 A A R Q K V R S Q F R S S S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 57.9 45.4 N.A. 81.7 N.A. N.A. 30.5 69.1 32.1 55.1 N.A. 31 32.1 30.4 36.7
Protein Similarity: 100 N.A. 62.9 51 N.A. 86.5 N.A. N.A. 32.8 78.9 43.6 64.4 N.A. 44.9 45 44 50.7
P-Site Identity: 100 N.A. 6.6 0 N.A. 100 N.A. N.A. 0 93.3 6.6 66.6 N.A. 6.6 46.6 0 53.3
P-Site Similarity: 100 N.A. 6.6 6.6 N.A. 100 N.A. N.A. 6.6 100 20 66.6 N.A. 20 60 6.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 25 9 9 9 9 0 9 17 0 0 17 9 0 0 % A
% Cys: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 0 0 9 0 0 0 9 50 % D
% Glu: 0 0 9 25 0 0 17 0 0 0 0 0 0 9 0 % E
% Phe: 0 9 0 9 0 0 0 0 9 50 0 9 0 0 0 % F
% Gly: 0 0 0 0 0 17 9 17 0 0 0 34 9 0 0 % G
% His: 0 0 9 0 0 9 0 0 0 0 34 0 9 17 0 % H
% Ile: 0 0 0 0 9 42 0 0 0 0 0 0 0 0 0 % I
% Lys: 17 0 0 0 50 0 0 0 9 0 0 0 0 0 0 % K
% Leu: 17 9 0 0 0 0 0 9 0 0 0 9 0 0 17 % L
% Met: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 9 9 9 0 9 0 0 0 9 0 0 0 9 9 % N
% Pro: 0 9 9 0 9 0 0 0 0 9 17 0 0 9 0 % P
% Gln: 0 0 0 17 9 0 0 0 9 9 9 0 9 9 9 % Q
% Arg: 0 9 34 0 0 0 50 9 34 17 17 9 0 0 0 % R
% Ser: 0 9 9 0 0 9 17 42 17 0 9 25 67 17 9 % S
% Thr: 0 25 9 9 0 0 0 0 9 0 9 0 0 25 9 % T
% Val: 9 0 9 0 0 9 9 17 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _