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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZFYVE28 All Species: 14.24
Human Site: S848 Identified Species: 28.48
UniProt: Q9HCC9 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCC9 NP_066023.1 887 96490 S848 S C G K I F C S R C S S H S A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001116192 715 75453 G677 D A H R R W V G T R P A G I L
Dog Lupus familis XP_545920 606 64606 L568 L K K V T Q S L R S A A L E D
Cat Felis silvestris
Mouse Mus musculus Q6ZPK7 905 99769 S866 S C G K I F C S R C S S H S A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521608 312 34972 R274 G R R P T P T R A A D P D D R
Chicken Gallus gallus XP_420832 912 101903 S873 S C G K I F C S R C S S H S A
Frog Xenopus laevis NP_001087164 538 61276 S500 C S Q C S A Y S S T L P Y I I
Zebra Danio Brachydanio rerio A0JMD2 969 106945 S930 S C G K I F C S R C S S H S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VB70 989 108781 G940 N C G G V F C G V C S N A S A
Honey Bee Apis mellifera XP_397433 1240 139257 G1199 N C G K V F C G R C S S N N V
Nematode Worm Caenorhab. elegans Q9TZD0 661 74507 V623 R V C N L C Y V H R L N S F G
Sea Urchin Strong. purpuratus XP_785516 997 110048 R919 S N S S H R S R R S N Y D D P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 57.9 45.4 N.A. 81.7 N.A. N.A. 30.5 69.1 32.1 55.1 N.A. 31 32.1 30.4 36.7
Protein Similarity: 100 N.A. 62.9 51 N.A. 86.5 N.A. N.A. 32.8 78.9 43.6 64.4 N.A. 44.9 45 44 50.7
P-Site Identity: 100 N.A. 0 6.6 N.A. 100 N.A. N.A. 0 100 6.6 100 N.A. 53.3 60 0 13.3
P-Site Similarity: 100 N.A. 20 20 N.A. 100 N.A. N.A. 0 100 13.3 100 N.A. 73.3 86.6 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 9 0 0 9 9 9 17 9 0 42 % A
% Cys: 9 50 9 9 0 9 50 0 0 50 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 0 9 0 17 17 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 50 0 0 0 0 0 0 0 9 0 % F
% Gly: 9 0 50 9 0 0 0 25 0 0 0 0 9 0 9 % G
% His: 0 0 9 0 9 0 0 0 9 0 0 0 34 0 0 % H
% Ile: 0 0 0 0 34 0 0 0 0 0 0 0 0 17 9 % I
% Lys: 0 9 9 42 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 0 0 9 0 0 9 0 0 17 0 9 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 17 9 0 9 0 0 0 0 0 0 9 17 9 9 0 % N
% Pro: 0 0 0 9 0 9 0 0 0 0 9 17 0 0 9 % P
% Gln: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 9 9 9 9 9 0 17 59 17 0 0 0 0 9 % R
% Ser: 42 9 9 9 9 0 17 42 9 17 50 42 9 42 0 % S
% Thr: 0 0 0 0 17 0 9 0 9 9 0 0 0 0 0 % T
% Val: 0 9 0 9 17 0 9 9 9 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 17 0 0 0 0 9 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _