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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE28
All Species:
20.91
Human Site:
S851
Identified Species:
41.82
UniProt:
Q9HCC9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCC9
NP_066023.1
887
96490
S851
K
I
F
C
S
R
C
S
S
H
S
A
P
L
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116192
715
75453
P680
R
R
W
V
G
T
R
P
A
G
I
L
V
R
G
Dog
Lupus familis
XP_545920
606
64606
A571
V
T
Q
S
L
R
S
A
A
L
E
D
C
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPK7
905
99769
S869
K
I
F
C
S
R
C
S
S
H
S
A
P
L
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521608
312
34972
D277
P
T
P
T
R
A
A
D
P
D
D
R
V
F
F
Chicken
Gallus gallus
XP_420832
912
101903
S876
K
I
F
C
S
R
C
S
S
H
S
A
P
L
P
Frog
Xenopus laevis
NP_001087164
538
61276
L503
C
S
A
Y
S
S
T
L
P
Y
I
I
S
T
H
Zebra Danio
Brachydanio rerio
A0JMD2
969
106945
S933
K
I
F
C
S
R
C
S
S
H
S
A
P
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB70
989
108781
S943
G
V
F
C
G
V
C
S
N
A
S
A
P
L
P
Honey Bee
Apis mellifera
XP_397433
1240
139257
S1202
K
V
F
C
G
R
C
S
S
N
N
V
P
L
P
Nematode Worm
Caenorhab. elegans
Q9TZD0
661
74507
L626
N
L
C
Y
V
H
R
L
N
S
F
G
C
N
E
Sea Urchin
Strong. purpuratus
XP_785516
997
110048
N922
S
H
R
S
R
R
S
N
Y
D
D
P
P
L
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
57.9
45.4
N.A.
81.7
N.A.
N.A.
30.5
69.1
32.1
55.1
N.A.
31
32.1
30.4
36.7
Protein Similarity:
100
N.A.
62.9
51
N.A.
86.5
N.A.
N.A.
32.8
78.9
43.6
64.4
N.A.
44.9
45
44
50.7
P-Site Identity:
100
N.A.
0
6.6
N.A.
100
N.A.
N.A.
0
100
6.6
100
N.A.
60
66.6
0
20
P-Site Similarity:
100
N.A.
20
20
N.A.
100
N.A.
N.A.
0
100
13.3
100
N.A.
73.3
86.6
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
9
9
17
9
0
42
0
9
0
% A
% Cys:
9
0
9
50
0
0
50
0
0
0
0
0
17
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
17
17
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% E
% Phe:
0
0
50
0
0
0
0
0
0
0
9
0
0
9
9
% F
% Gly:
9
0
0
0
25
0
0
0
0
9
0
9
0
0
9
% G
% His:
0
9
0
0
0
9
0
0
0
34
0
0
0
0
9
% H
% Ile:
0
34
0
0
0
0
0
0
0
0
17
9
0
0
0
% I
% Lys:
42
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
0
0
9
0
0
17
0
9
0
9
0
59
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
9
17
9
9
0
0
9
0
% N
% Pro:
9
0
9
0
0
0
0
9
17
0
0
9
59
0
50
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
9
9
0
17
59
17
0
0
0
0
9
0
9
0
% R
% Ser:
9
9
0
17
42
9
17
50
42
9
42
0
9
0
0
% S
% Thr:
0
17
0
9
0
9
9
0
0
0
0
0
0
9
0
% T
% Val:
9
17
0
9
9
9
0
0
0
0
0
9
17
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
17
0
0
0
0
9
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _