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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOV10 All Species: 17.88
Human Site: S496 Identified Species: 35.76
UniProt: Q9HCE1 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCE1 NP_001123551.1 1003 113671 S496 K L K L Y D R S L E S N P E Q
Chimpanzee Pan troglodytes XP_513630 1028 116494 S521 K L K L Y D R S L E S N P E Q
Rhesus Macaque Macaca mulatta XP_001108355 1003 113585 S496 K L K L Y D R S L E S N P E Q
Dog Lupus familis XP_540337 1131 127423 S624 K L K L Y D R S L E S N P E Q
Cat Felis silvestris
Mouse Mus musculus P23249 1004 113564 S497 K F K L Y D R S L E S N P E Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKD7 967 109032 K488 Q P R W F D R K V E A N E E Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LXK4 1013 116388 K522 A L R L F D Q K L E K N P E Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q6J5K9 1274 144870 N781 D S K L E W Y N Q S L N S I Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788148 953 108102 K518 T R T L F D Q K L S A N M E Q
Poplar Tree Populus trichocarpa XP_002332671 894 100931 H469 L L S E E A V H I Q E K E I F
Maize Zea mays NP_001168662 973 109762 L499 K F C F F Q D L V F K C P P L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GYD9 1002 113345 L503 R F C F F D E L I F K C P P L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 99 84 N.A. 91.1 N.A. N.A. N.A. 47.5 N.A. 43.8 N.A. 27.8 N.A. N.A. 37.3
Protein Similarity: 100 97.5 99.5 86.2 N.A. 95 N.A. N.A. N.A. 63.2 N.A. 62.4 N.A. 45.1 N.A. N.A. 54.7
P-Site Identity: 100 100 100 100 N.A. 93.3 N.A. N.A. N.A. 40 N.A. 60 N.A. 26.6 N.A. N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. N.A. 73.3 N.A. 80 N.A. 33.3 N.A. N.A. 60
Percent
Protein Identity: 32.5 32.9 N.A. 29 N.A. N.A.
Protein Similarity: 48.9 50.8 N.A. 48.5 N.A. N.A.
P-Site Identity: 6.6 13.3 N.A. 13.3 N.A. N.A.
P-Site Similarity: 20 26.6 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 9 0 0 0 0 17 0 0 0 0 % A
% Cys: 0 0 17 0 0 0 0 0 0 0 0 17 0 0 0 % C
% Asp: 9 0 0 0 0 75 9 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 9 17 0 9 0 0 59 9 0 17 67 0 % E
% Phe: 0 25 0 17 42 0 0 0 0 17 0 0 0 0 9 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 17 0 0 0 0 17 0 % I
% Lys: 50 0 50 0 0 0 0 25 0 0 25 9 0 0 0 % K
% Leu: 9 50 0 67 0 0 0 17 59 0 9 0 0 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 0 75 0 0 0 % N
% Pro: 0 9 0 0 0 0 0 0 0 0 0 0 67 17 0 % P
% Gln: 9 0 0 0 0 9 17 0 9 9 0 0 0 0 75 % Q
% Arg: 9 9 17 0 0 0 50 0 0 0 0 0 0 0 0 % R
% Ser: 0 9 9 0 0 0 0 42 0 17 42 0 9 0 0 % S
% Thr: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 9 0 17 0 0 0 0 0 0 % V
% Trp: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 42 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _