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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOV10 All Species: 20
Human Site: Y117 Identified Species: 40
UniProt: Q9HCE1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCE1 NP_001123551.1 1003 113671 Y117 I F Y D R A E Y L H G K H G V
Chimpanzee Pan troglodytes XP_513630 1028 116494 Y142 I F Y D R A E Y L H G K H G V
Rhesus Macaque Macaca mulatta XP_001108355 1003 113585 Y117 I F Y D R A E Y L H G K H G V
Dog Lupus familis XP_540337 1131 127423 Y245 I F Y D R A E Y L H G K H G V
Cat Felis silvestris
Mouse Mus musculus P23249 1004 113564 Y117 I F H D R A E Y L H G K H G V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKD7 967 109032 S115 S G P P A P Q S R A K K W A E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LXK4 1013 116388 V125 R V S D P S S V P E P E N R V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q6J5K9 1274 144870 S268 I S Q R L A S S I D V E T E Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788148 953 108102 R117 Q G S T S P T R A P G D G G R
Poplar Tree Populus trichocarpa XP_002332671 894 100931 V118 E G F M D F S V M E D R M L Q
Maize Zea mays NP_001168662 973 109762 E109 P S N G A S E E E K Q A F L A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GYD9 1002 113345 L120 C F Y E T F T L E D R M L E P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 99 84 N.A. 91.1 N.A. N.A. N.A. 47.5 N.A. 43.8 N.A. 27.8 N.A. N.A. 37.3
Protein Similarity: 100 97.5 99.5 86.2 N.A. 95 N.A. N.A. N.A. 63.2 N.A. 62.4 N.A. 45.1 N.A. N.A. 54.7
P-Site Identity: 100 100 100 100 N.A. 93.3 N.A. N.A. N.A. 6.6 N.A. 13.3 N.A. 13.3 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. N.A. 13.3 N.A. 33.3 N.A. 26.6 N.A. N.A. 13.3
Percent
Protein Identity: 32.5 32.9 N.A. 29 N.A. N.A.
Protein Similarity: 48.9 50.8 N.A. 48.5 N.A. N.A.
P-Site Identity: 0 6.6 N.A. 13.3 N.A. N.A.
P-Site Similarity: 20 13.3 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 17 50 0 0 9 9 0 9 0 9 9 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 50 9 0 0 0 0 17 9 9 0 0 0 % D
% Glu: 9 0 0 9 0 0 50 9 17 17 0 17 0 17 9 % E
% Phe: 0 50 9 0 0 17 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 25 0 9 0 0 0 0 0 0 50 0 9 50 0 % G
% His: 0 0 9 0 0 0 0 0 0 42 0 0 42 0 0 % H
% Ile: 50 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 9 9 50 0 0 0 % K
% Leu: 0 0 0 0 9 0 0 9 42 0 0 0 9 17 0 % L
% Met: 0 0 0 9 0 0 0 0 9 0 0 9 9 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 9 0 9 9 9 17 0 0 9 9 9 0 0 0 9 % P
% Gln: 9 0 9 0 0 0 9 0 0 0 9 0 0 0 9 % Q
% Arg: 9 0 0 9 42 0 0 9 9 0 9 9 0 9 9 % R
% Ser: 9 17 17 0 9 17 25 17 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 9 9 0 17 0 0 0 0 0 9 0 0 % T
% Val: 0 9 0 0 0 0 0 17 0 0 9 0 0 0 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 42 0 0 0 0 42 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _