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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGEF10L
All Species:
12.12
Human Site:
Y215
Identified Species:
26.67
UniProt:
Q9HCE6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCE6
NP_001011722.2
1279
140365
Y215
L
T
R
L
K
E
R
Y
A
R
T
K
R
D
I
Chimpanzee
Pan troglodytes
XP_001156394
1277
139760
L213
L
T
T
W
S
F
S
L
A
M
A
K
A
H
L
Rhesus Macaque
Macaca mulatta
XP_001089943
1277
140052
Y213
L
T
R
L
K
E
R
Y
A
R
T
K
R
D
I
Dog
Lupus familis
XP_544536
1054
115285
P91
P
M
P
D
G
L
S
P
Q
Q
V
V
R
R
H
Cat
Felis silvestris
Mouse
Mus musculus
A2AWP8
1280
139968
Y213
L
T
R
L
K
E
R
Y
V
R
T
K
R
D
I
Rat
Rattus norvegicus
XP_002725258
1373
150917
C328
L
T
R
F
K
A
H
C
E
E
K
M
R
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506297
869
95275
Chicken
Gallus gallus
XP_001235643
1358
152128
Y309
L
T
R
L
K
E
H
Y
E
K
K
M
K
D
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696040
1281
142150
C219
V
R
R
L
K
Q
R
C
V
Q
T
R
R
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397118
1554
173602
C375
L
H
K
A
R
T
L
C
D
K
W
R
P
Q
N
Nematode Worm
Caenorhab. elegans
Q21653
1182
132752
H209
G
I
S
T
R
L
G
H
P
R
G
V
M
Q
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
98.1
77
N.A.
91.5
41.1
N.A.
43.2
41.2
N.A.
55.5
N.A.
N.A.
22.3
20.7
N.A.
Protein Similarity:
100
97.5
98.5
79.1
N.A.
94.5
57.7
N.A.
51.6
59.7
N.A.
71.4
N.A.
N.A.
41.4
39.2
N.A.
P-Site Identity:
100
26.6
100
6.6
N.A.
93.3
33.3
N.A.
0
53.3
N.A.
40
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
100
33.3
100
13.3
N.A.
93.3
40
N.A.
0
73.3
N.A.
80
N.A.
N.A.
33.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
10
0
0
28
0
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
28
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
10
0
0
0
0
37
0
% D
% Glu:
0
0
0
0
0
37
0
0
19
10
0
0
0
10
0
% E
% Phe:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
10
% F
% Gly:
10
0
0
0
10
0
10
0
0
0
10
0
0
10
0
% G
% His:
0
10
0
0
0
0
19
10
0
0
0
0
0
10
10
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
28
% I
% Lys:
0
0
10
0
55
0
0
0
0
19
19
37
10
0
0
% K
% Leu:
64
0
0
46
0
19
10
10
0
0
0
0
0
0
37
% L
% Met:
0
10
0
0
0
0
0
0
0
10
0
19
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
10
0
10
0
0
0
0
10
10
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
10
19
0
0
0
19
0
% Q
% Arg:
0
10
55
0
19
0
37
0
0
37
0
19
55
10
0
% R
% Ser:
0
0
10
0
10
0
19
0
0
0
0
0
0
0
0
% S
% Thr:
0
55
10
10
0
10
0
0
0
0
37
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
19
0
10
19
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
37
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _