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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMURF1 All Species: 37.58
Human Site: S136 Identified Species: 68.89
UniProt: Q9HCE7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCE7 NP_065162.1 757 86114 S136 V R G Q I V V S L Q T R D R I
Chimpanzee Pan troglodytes XP_528043 794 90193 S173 V R G Q I V V S L Q T R D R I
Rhesus Macaque Macaca mulatta XP_001109913 898 102762 S285 V R G Q I V V S L Q S R D R I
Dog Lupus familis XP_851049 740 84637 T123 A I S R L K D T G Y Q R L D L
Cat Felis silvestris
Mouse Mus musculus Q9CUN6 731 83337 S136 V R G Q I V V S L Q T R D R I
Rat Rattus norvegicus Q62940 887 102376 K203 V K G Y L R L K M T Y L P K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512326 750 85604 T134 A I S R L K D T G Y Q R L D L
Chicken Gallus gallus XP_414794 729 83344 S136 V R G Q I V V S L Q T R D R I
Frog Xenopus laevis Q9PUN2 731 83241 S136 V R G Q I V V S L Q T R D R I
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 S135 V R G Q I V V S L Q S R D R I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V853 1061 115657 S134 V R G Q I I I S L L S K D G P
Honey Bee Apis mellifera XP_396318 779 88933 S136 V K G E V V V S L L S R D G H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39940 809 91798 V134 V S G R L I V V L S K L P S S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.9 59.5 91.9 N.A. 95.2 32 N.A. 92.7 94.1 87.7 68.2 N.A. 44.6 59.3 N.A. N.A.
Protein Similarity: 100 94.8 67.9 93.9 N.A. 95.5 47.2 N.A. 94.4 95.6 92.2 79.3 N.A. 55.2 70.5 N.A. N.A.
P-Site Identity: 100 100 93.3 6.6 N.A. 100 13.3 N.A. 6.6 100 100 93.3 N.A. 53.3 53.3 N.A. N.A.
P-Site Similarity: 100 100 100 33.3 N.A. 100 46.6 N.A. 33.3 100 100 100 N.A. 80 80 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 38.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 54.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 16 0 0 0 0 0 70 16 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 85 0 0 0 0 0 16 0 0 0 0 16 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 16 0 0 62 16 8 0 0 0 0 0 0 0 54 % I
% Lys: 0 16 0 0 0 16 0 8 0 0 8 8 0 8 0 % K
% Leu: 0 0 0 0 31 0 8 0 77 16 0 16 16 0 16 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 16 0 8 % P
% Gln: 0 0 0 62 0 0 0 0 0 54 16 0 0 0 0 % Q
% Arg: 0 62 0 24 0 8 0 0 0 0 0 77 0 54 0 % R
% Ser: 0 8 16 0 0 0 0 70 0 8 31 0 0 8 8 % S
% Thr: 0 0 0 0 0 0 0 16 0 8 39 0 0 0 0 % T
% Val: 85 0 0 0 8 62 70 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 16 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _