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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMURF1
All Species:
9.09
Human Site:
S185
Identified Species:
16.67
UniProt:
Q9HCE7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCE7
NP_065162.1
757
86114
S185
E
P
A
P
Y
T
D
S
T
G
A
A
A
G
G
Chimpanzee
Pan troglodytes
XP_528043
794
90193
S222
E
P
A
P
Y
T
D
S
T
G
A
A
A
G
G
Rhesus Macaque
Macaca mulatta
XP_001109913
898
102762
Q334
N
H
I
T
R
T
T
Q
W
E
R
P
T
R
P
Dog
Lupus familis
XP_851049
740
84637
G172
R
G
L
V
E
N
E
G
T
V
Y
E
D
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CUN6
731
83337
G185
E
P
A
P
Y
T
D
G
T
G
A
A
A
G
G
Rat
Rattus norvegicus
Q62940
887
102376
W252
P
S
P
L
P
P
G
W
E
E
R
Q
D
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512326
750
85604
G183
R
G
L
L
E
N
E
G
T
V
Y
E
D
S
G
Chicken
Gallus gallus
XP_414794
729
83344
T185
E
P
A
P
Y
T
D
T
T
G
A
A
G
G
G
Frog
Xenopus laevis
Q9PUN2
731
83241
G185
E
P
A
P
Y
T
D
G
P
G
A
A
G
G
G
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
Q184
N
H
I
T
R
S
T
Q
W
E
R
P
T
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V853
1061
115657
V183
R
R
T
D
N
G
R
V
Y
Y
V
N
H
A
T
Honey Bee
Apis mellifera
XP_396318
779
88933
Y185
T
R
S
G
R
L
Y
Y
V
N
H
Y
T
R
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
R183
H
S
T
S
H
P
S
R
G
T
A
Q
A
V
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.9
59.5
91.9
N.A.
95.2
32
N.A.
92.7
94.1
87.7
68.2
N.A.
44.6
59.3
N.A.
N.A.
Protein Similarity:
100
94.8
67.9
93.9
N.A.
95.5
47.2
N.A.
94.4
95.6
92.2
79.3
N.A.
55.2
70.5
N.A.
N.A.
P-Site Identity:
100
100
6.6
13.3
N.A.
93.3
0
N.A.
13.3
86.6
80
0
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
100
6.6
20
N.A.
93.3
0
N.A.
20
93.3
80
6.6
N.A.
0
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
39
0
0
0
0
0
0
0
47
39
31
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
39
0
0
0
0
0
24
0
0
% D
% Glu:
39
0
0
0
16
0
16
0
8
24
0
16
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
16
0
8
0
8
8
31
8
39
0
0
16
39
54
% G
% His:
8
16
0
0
8
0
0
0
0
0
8
0
8
0
0
% H
% Ile:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
16
16
0
8
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
0
0
0
8
16
0
0
0
8
0
8
0
0
0
% N
% Pro:
8
39
8
39
8
16
0
0
8
0
0
16
0
0
16
% P
% Gln:
0
0
0
0
0
0
0
16
0
0
0
16
0
0
0
% Q
% Arg:
24
16
0
0
24
0
8
8
0
0
24
0
0
24
0
% R
% Ser:
0
16
8
8
0
8
8
16
0
0
0
0
0
16
0
% S
% Thr:
8
0
16
16
0
47
16
8
47
8
0
0
24
0
16
% T
% Val:
0
0
0
8
0
0
0
8
8
16
8
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
8
16
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
39
0
8
8
8
8
16
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _