KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMURF1
All Species:
5.76
Human Site:
S271
Identified Species:
10.56
UniProt:
Q9HCE7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCE7
NP_065162.1
757
86114
S271
D
P
R
I
P
S
P
S
G
T
I
P
G
G
D
Chimpanzee
Pan troglodytes
XP_528043
794
90193
S308
D
P
R
I
P
S
P
S
G
T
I
P
G
G
D
Rhesus Macaque
Macaca mulatta
XP_001109913
898
102762
F419
T
Q
Q
G
Q
V
Y
F
L
H
T
Q
T
G
V
Dog
Lupus familis
XP_851049
740
84637
T257
E
G
Y
E
Q
R
T
T
V
Q
G
Q
V
Y
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9CUN6
731
83337
L271
D
P
R
I
P
R
D
L
N
S
V
N
C
D
E
Rat
Rattus norvegicus
Q62940
887
102376
G343
A
V
Q
S
P
P
S
G
H
P
D
V
Q
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512326
750
85604
T267
E
G
Y
E
Q
R
T
T
V
Q
G
Q
V
Y
F
Chicken
Gallus gallus
XP_414794
729
83344
L270
D
P
R
I
P
R
D
L
N
S
V
N
C
D
E
Frog
Xenopus laevis
Q9PUN2
731
83241
L270
D
P
R
I
P
R
D
L
N
S
V
N
C
D
D
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
L288
D
P
R
V
P
R
D
L
S
N
V
N
C
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V853
1061
115657
K288
S
A
T
T
T
P
G
K
K
T
S
S
S
N
S
Honey Bee
Apis mellifera
XP_396318
779
88933
P276
R
R
Y
D
P
P
Q
P
P
D
L
P
R
G
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
E266
R
P
T
L
D
Q
T
E
A
E
R
G
N
Q
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.9
59.5
91.9
N.A.
95.2
32
N.A.
92.7
94.1
87.7
68.2
N.A.
44.6
59.3
N.A.
N.A.
Protein Similarity:
100
94.8
67.9
93.9
N.A.
95.5
47.2
N.A.
94.4
95.6
92.2
79.3
N.A.
55.2
70.5
N.A.
N.A.
P-Site Identity:
100
100
6.6
0
N.A.
33.3
6.6
N.A.
0
33.3
40
26.6
N.A.
6.6
20
N.A.
N.A.
P-Site Similarity:
100
100
13.3
13.3
N.A.
53.3
13.3
N.A.
13.3
53.3
53.3
46.6
N.A.
6.6
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
31
0
0
% C
% Asp:
47
0
0
8
8
0
31
0
0
8
8
0
0
24
24
% D
% Glu:
16
0
0
16
0
0
0
8
0
8
0
0
0
8
24
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
16
% F
% Gly:
0
16
0
8
0
0
8
8
16
0
16
8
16
31
0
% G
% His:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% H
% Ile:
0
0
0
39
0
0
0
0
0
0
16
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
0
0
31
8
0
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
24
8
0
31
8
8
0
% N
% Pro:
0
54
0
0
62
24
16
8
8
8
0
24
0
0
0
% P
% Gln:
0
8
16
0
24
8
8
0
0
16
0
24
8
8
0
% Q
% Arg:
16
8
47
0
0
47
0
0
0
0
8
0
8
0
8
% R
% Ser:
8
0
0
8
0
16
8
16
8
24
8
8
8
0
8
% S
% Thr:
8
0
16
8
8
0
24
16
0
24
8
0
8
0
0
% T
% Val:
0
8
0
8
0
8
0
0
16
0
31
8
16
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
24
0
0
0
8
0
0
0
0
0
0
16
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _