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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMURF1
All Species:
14.24
Human Site:
S316
Identified Species:
26.11
UniProt:
Q9HCE7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCE7
NP_065162.1
757
86114
S316
P
P
G
W
E
V
R
S
T
V
S
G
R
I
Y
Chimpanzee
Pan troglodytes
XP_528043
794
90193
S353
P
P
G
W
E
V
R
S
T
V
S
G
R
I
Y
Rhesus Macaque
Macaca mulatta
XP_001109913
898
102762
R462
I
R
N
T
A
T
G
R
V
Y
F
V
D
H
N
Dog
Lupus familis
XP_851049
740
84637
S302
P
P
G
W
E
V
R
S
T
V
S
G
R
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9CUN6
731
83337
H315
F
T
D
P
R
L
H
H
I
M
N
H
Q
C
Q
Rat
Rattus norvegicus
Q62940
887
102376
Q412
P
P
G
W
E
E
K
Q
D
D
R
G
R
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512326
750
85604
S312
P
P
G
W
E
V
R
S
T
V
S
G
R
I
Y
Chicken
Gallus gallus
XP_414794
729
83344
H314
F
T
D
P
R
L
H
H
I
M
N
H
Q
C
Q
Frog
Xenopus laevis
Q9PUN2
731
83241
H314
F
T
D
P
R
L
H
H
I
I
N
H
Q
S
Q
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
S331
Q
F
T
D
P
R
L
S
A
N
L
H
L
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V853
1061
115657
K571
P
S
G
W
E
Q
R
K
T
A
S
G
R
V
Y
Honey Bee
Apis mellifera
XP_396318
779
88933
Q334
P
S
G
W
E
M
R
Q
T
Q
S
G
R
V
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
F341
P
S
G
W
E
Q
R
F
T
P
E
G
R
A
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.9
59.5
91.9
N.A.
95.2
32
N.A.
92.7
94.1
87.7
68.2
N.A.
44.6
59.3
N.A.
N.A.
Protein Similarity:
100
94.8
67.9
93.9
N.A.
95.5
47.2
N.A.
94.4
95.6
92.2
79.3
N.A.
55.2
70.5
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
0
53.3
N.A.
100
0
0
6.6
N.A.
66.6
66.6
N.A.
N.A.
P-Site Similarity:
100
100
0
100
N.A.
26.6
60
N.A.
100
26.6
26.6
13.3
N.A.
73.3
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% C
% Asp:
0
0
24
8
0
0
0
0
8
8
0
0
8
0
0
% D
% Glu:
0
0
0
0
62
8
0
0
0
0
8
0
0
0
0
% E
% Phe:
24
8
0
0
0
0
0
8
0
0
8
0
0
0
0
% F
% Gly:
0
0
62
0
0
0
8
0
0
0
0
62
0
0
0
% G
% His:
0
0
0
0
0
0
24
24
0
0
0
31
0
8
0
% H
% Ile:
8
0
0
0
0
0
0
0
24
8
0
0
0
31
0
% I
% Lys:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
24
8
0
0
0
8
0
8
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
16
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
8
24
0
0
0
8
% N
% Pro:
62
39
0
24
8
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
16
0
16
0
8
0
0
24
0
24
% Q
% Arg:
0
8
0
0
24
8
54
8
0
0
8
0
62
0
0
% R
% Ser:
0
24
0
0
0
0
0
39
0
0
47
0
0
16
0
% S
% Thr:
0
24
8
8
0
8
0
0
54
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
31
0
0
8
31
0
8
0
24
0
% V
% Trp:
0
0
0
62
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
62
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _