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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMURF1 All Species: 36.06
Human Site: S50 Identified Species: 66.11
UniProt: Q9HCE7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCE7 NP_065162.1 757 86114 S50 D G S G Q C H S T D T V K N T
Chimpanzee Pan troglodytes XP_528043 794 90193 S87 D G S G Q C H S T D T V K N T
Rhesus Macaque Macaca mulatta XP_001109913 898 102762 S199 D G S G Q C H S T D T V K N T
Dog Lupus familis XP_851049 740 84637 N40 G G R S Q S Q N A M Y G L P D
Cat Felis silvestris
Mouse Mus musculus Q9CUN6 731 83337 S50 D G S G Q C H S T D T V K N T
Rat Rattus norvegicus Q62940 887 102376 Q116 S G V L T S V Q T K T I K K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512326 750 85604 K51 C A K N L A K K D F F R L P D
Chicken Gallus gallus XP_414794 729 83344 S50 D G S G Q C H S T D T V K N T
Frog Xenopus laevis Q9PUN2 731 83241 S50 D G S G Q C H S T D T V K N T
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 S49 D G S G Q C H S T D T V R N T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V853 1061 115657 S50 D G T G Q V Y S T E I S K S S
Honey Bee Apis mellifera XP_396318 779 88933 S50 D G S G Q C H S T H T C K A T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39940 809 91798 S39 I D G Y Q T K S T S A A K K T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.9 59.5 91.9 N.A. 95.2 32 N.A. 92.7 94.1 87.7 68.2 N.A. 44.6 59.3 N.A. N.A.
Protein Similarity: 100 94.8 67.9 93.9 N.A. 95.5 47.2 N.A. 94.4 95.6 92.2 79.3 N.A. 55.2 70.5 N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. 100 26.6 N.A. 0 100 100 93.3 N.A. 46.6 80 N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 100 40 N.A. 0 100 100 100 N.A. 80 80 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 38.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 54.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 8 0 0 8 0 8 8 0 8 0 % A
% Cys: 8 0 0 0 0 62 0 0 0 0 0 8 0 0 0 % C
% Asp: 70 8 0 0 0 0 0 0 8 54 0 0 0 0 16 % D
% Glu: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % F
% Gly: 8 85 8 70 0 0 0 0 0 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 62 0 0 8 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % I
% Lys: 0 0 8 0 0 0 16 8 0 8 0 0 77 16 0 % K
% Leu: 0 0 0 8 8 0 0 0 0 0 0 0 16 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 8 0 0 0 0 0 54 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % P
% Gln: 0 0 0 0 85 0 8 8 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 8 8 0 0 % R
% Ser: 8 0 62 8 0 16 0 77 0 8 0 8 0 8 16 % S
% Thr: 0 0 8 0 8 8 0 0 85 0 70 0 0 0 70 % T
% Val: 0 0 8 0 0 8 8 0 0 0 0 54 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 8 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _