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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMURF1
All Species:
37.58
Human Site:
S538
Identified Species:
68.89
UniProt:
Q9HCE7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCE7
NP_065162.1
757
86114
S538
V
D
P
E
L
H
K
S
L
V
W
I
L
E
N
Chimpanzee
Pan troglodytes
XP_528043
794
90193
S575
V
D
P
E
L
H
K
S
L
V
W
I
L
E
N
Rhesus Macaque
Macaca mulatta
XP_001109913
898
102762
S682
V
D
P
D
L
H
N
S
L
V
W
I
L
E
N
Dog
Lupus familis
XP_851049
740
84637
S524
V
D
P
E
L
H
K
S
L
V
W
I
L
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9CUN6
731
83337
D520
L
V
W
I
L
E
N
D
I
T
P
V
L
D
H
Rat
Rattus norvegicus
Q62940
887
102376
S671
V
D
S
E
Y
Y
S
S
L
R
W
I
L
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512326
750
85604
S534
V
D
P
E
L
H
K
S
L
V
W
I
L
E
N
Chicken
Gallus gallus
XP_414794
729
83344
D521
L
V
W
I
L
E
N
D
I
T
P
V
L
D
H
Frog
Xenopus laevis
Q9PUN2
731
83241
D520
L
V
W
I
L
E
N
D
I
T
S
V
L
D
H
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
S549
V
D
P
D
L
H
N
S
L
V
W
I
L
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V853
1061
115657
S841
V
D
P
D
L
H
R
S
L
T
W
M
L
E
S
Honey Bee
Apis mellifera
XP_396318
779
88933
S562
V
D
P
E
L
H
R
S
L
T
W
M
L
E
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
S594
V
D
A
E
V
Y
N
S
L
N
W
M
L
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.9
59.5
91.9
N.A.
95.2
32
N.A.
92.7
94.1
87.7
68.2
N.A.
44.6
59.3
N.A.
N.A.
Protein Similarity:
100
94.8
67.9
93.9
N.A.
95.5
47.2
N.A.
94.4
95.6
92.2
79.3
N.A.
55.2
70.5
N.A.
N.A.
P-Site Identity:
100
100
86.6
100
N.A.
13.3
66.6
N.A.
100
13.3
13.3
80
N.A.
66.6
80
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
46.6
73.3
N.A.
100
46.6
46.6
93.3
N.A.
93.3
93.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
77
0
24
0
0
0
24
0
0
0
0
0
31
0
% D
% Glu:
0
0
0
54
0
24
0
0
0
0
0
0
0
70
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
62
0
0
0
0
0
0
0
0
24
% H
% Ile:
0
0
0
24
0
0
0
0
24
0
0
54
0
0
0
% I
% Lys:
0
0
0
0
0
0
31
0
0
0
0
0
0
0
0
% K
% Leu:
24
0
0
0
85
0
0
0
77
0
0
0
100
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
24
0
0
0
% M
% Asn:
0
0
0
0
0
0
47
0
0
8
0
0
0
0
70
% N
% Pro:
0
0
62
0
0
0
0
0
0
0
16
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
16
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
8
77
0
0
8
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
39
0
0
0
0
0
% T
% Val:
77
24
0
0
8
0
0
0
0
47
0
24
0
0
0
% V
% Trp:
0
0
24
0
0
0
0
0
0
0
77
0
0
0
0
% W
% Tyr:
0
0
0
0
8
16
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _