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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMURF1
All Species:
40.91
Human Site:
S736
Identified Species:
75
UniProt:
Q9HCE7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCE7
NP_065162.1
757
86114
S736
I
D
I
P
P
Y
E
S
Y
E
K
L
Y
E
K
Chimpanzee
Pan troglodytes
XP_528043
794
90193
S773
I
D
I
P
P
Y
E
S
Y
E
K
L
Y
E
K
Rhesus Macaque
Macaca mulatta
XP_001109913
898
102762
S877
I
D
I
P
P
Y
E
S
Y
E
K
L
Y
E
K
Dog
Lupus familis
XP_851049
740
84637
S719
I
D
I
P
P
Y
E
S
Y
E
K
L
Y
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CUN6
731
83337
S710
I
D
I
P
P
Y
E
S
Y
E
K
L
Y
E
K
Rat
Rattus norvegicus
Q62940
887
102376
S865
L
D
L
P
P
Y
E
S
F
D
E
L
W
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512326
750
85604
S729
I
D
I
P
P
Y
E
S
Y
E
K
L
Y
E
K
Chicken
Gallus gallus
XP_414794
729
83344
S708
I
D
I
P
P
Y
E
S
Y
E
K
L
Y
E
K
Frog
Xenopus laevis
Q9PUN2
731
83241
S710
I
D
I
P
P
Y
E
S
Y
E
K
L
Y
E
K
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
S744
I
D
I
P
P
Y
E
S
Y
D
K
L
Y
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V853
1061
115657
E1039
R
I
D
L
P
P
Y
E
T
Y
Q
L
L
C
D
Honey Bee
Apis mellifera
XP_396318
779
88933
P757
I
D
I
P
E
S
Y
P
S
Y
Q
K
M
L
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
D788
V
D
L
P
Q
Y
V
D
Y
D
S
M
K
Q
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.9
59.5
91.9
N.A.
95.2
32
N.A.
92.7
94.1
87.7
68.2
N.A.
44.6
59.3
N.A.
N.A.
Protein Similarity:
100
94.8
67.9
93.9
N.A.
95.5
47.2
N.A.
94.4
95.6
92.2
79.3
N.A.
55.2
70.5
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
53.3
N.A.
100
100
100
86.6
N.A.
13.3
26.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
20
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
93
8
0
0
0
0
8
0
24
0
0
0
16
16
% D
% Glu:
0
0
0
0
8
0
77
8
0
62
8
0
0
62
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
77
8
77
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
70
8
8
0
85
% K
% Leu:
8
0
16
8
0
0
0
0
0
0
0
85
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
93
85
8
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
16
0
0
8
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
77
8
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
85
16
0
77
16
0
0
70
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _