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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMURF1
All Species:
34.55
Human Site:
Y66
Identified Species:
63.33
UniProt:
Q9HCE7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCE7
NP_065162.1
757
86114
Y66
D
P
K
W
N
Q
H
Y
D
L
Y
V
G
K
T
Chimpanzee
Pan troglodytes
XP_528043
794
90193
Y103
D
P
K
W
N
Q
H
Y
D
L
Y
V
G
K
T
Rhesus Macaque
Macaca mulatta
XP_001109913
898
102762
Y215
D
P
K
W
N
Q
H
Y
D
L
Y
I
G
K
S
Dog
Lupus familis
XP_851049
740
84637
G56
F
A
K
I
V
V
D
G
S
G
Q
C
H
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CUN6
731
83337
Y66
D
P
K
W
N
Q
H
Y
D
L
Y
V
G
K
T
Rat
Rattus norvegicus
Q62940
887
102376
I132
N
P
K
W
N
E
E
I
L
F
R
V
L
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512326
750
85604
G67
F
A
K
I
V
V
D
G
S
G
Q
C
H
S
T
Chicken
Gallus gallus
XP_414794
729
83344
Y66
D
P
K
W
N
Q
H
Y
D
L
Y
V
G
K
T
Frog
Xenopus laevis
Q9PUN2
731
83241
Y66
D
P
K
W
N
Q
H
Y
D
L
Y
V
G
K
M
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
Y65
D
P
K
W
N
Q
H
Y
D
L
Y
I
G
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V853
1061
115657
Y66
D
P
K
W
N
A
H
Y
D
L
F
L
G
I
G
Honey Bee
Apis mellifera
XP_396318
779
88933
Y66
D
P
M
W
N
Q
H
Y
D
L
Y
I
G
K
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
F55
N
P
Y
W
N
E
T
F
K
F
D
D
I
N
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.9
59.5
91.9
N.A.
95.2
32
N.A.
92.7
94.1
87.7
68.2
N.A.
44.6
59.3
N.A.
N.A.
Protein Similarity:
100
94.8
67.9
93.9
N.A.
95.5
47.2
N.A.
94.4
95.6
92.2
79.3
N.A.
55.2
70.5
N.A.
N.A.
P-Site Identity:
100
100
86.6
13.3
N.A.
100
33.3
N.A.
13.3
100
93.3
86.6
N.A.
66.6
80
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
46.6
N.A.
13.3
100
93.3
100
N.A.
80
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% C
% Asp:
70
0
0
0
0
0
16
0
70
0
8
8
0
0
8
% D
% Glu:
0
0
0
0
0
16
8
0
0
0
0
0
0
0
8
% E
% Phe:
16
0
0
0
0
0
0
8
0
16
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
16
0
16
0
0
70
0
8
% G
% His:
0
0
0
0
0
0
70
0
0
0
0
0
16
0
0
% H
% Ile:
0
0
0
16
0
0
0
8
0
0
0
24
8
8
0
% I
% Lys:
0
0
85
0
0
0
0
0
8
0
0
0
0
62
0
% K
% Leu:
0
0
0
0
0
0
0
0
8
70
0
8
8
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
16
0
0
0
85
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
85
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
62
0
0
0
0
16
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
16
0
0
0
0
16
16
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
47
% T
% Val:
0
0
0
0
16
16
0
0
0
0
0
47
0
0
0
% V
% Trp:
0
0
0
85
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
70
0
0
62
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _