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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANO8
All Species:
20.91
Human Site:
Y433
Identified Species:
51.11
UniProt:
Q9HCE9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCE9
NP_066010.1
1232
136034
Y433
N
Y
R
L
E
S
A
Y
E
K
H
L
I
I
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001114998
635
73571
W9
S
K
R
K
P
K
K
W
L
K
N
R
I
I
A
Dog
Lupus familis
XP_541955
1107
123145
Y433
N
Y
R
L
E
S
A
Y
E
K
H
L
I
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6PB70
1060
119082
Y433
N
Y
R
L
E
S
T
Y
E
R
H
L
I
I
K
Rat
Rattus norvegicus
XP_002725222
941
106516
T315
E
L
A
Y
K
W
G
T
L
D
S
P
G
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518745
1242
139890
Y575
N
Y
R
L
Q
S
A
Y
E
K
H
L
I
I
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q4V8U5
646
74505
A19
A
S
P
F
T
P
L
A
V
L
E
L
A
H
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995719
1259
138367
Y490
N
Y
R
L
Q
S
K
Y
E
N
H
L
I
A
K
Honey Bee
Apis mellifera
XP_392436
1107
124093
Y469
N
Y
R
L
D
T
E
Y
E
N
H
L
I
Y
K
Nematode Worm
Caenorhab. elegans
NP_872101
837
96736
D211
Q
K
W
V
F
S
I
D
E
Q
P
I
D
Q
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
20.8
84.8
N.A.
76.6
70.5
N.A.
64.4
N.A.
N.A.
20.6
N.A.
24.5
29.2
29.1
N.A.
Protein Similarity:
100
N.A.
31
86.4
N.A.
79.8
72.5
N.A.
72.8
N.A.
N.A.
31
N.A.
39.1
43.9
42.9
N.A.
P-Site Identity:
100
N.A.
26.6
100
N.A.
86.6
0
N.A.
93.3
N.A.
N.A.
6.6
N.A.
73.3
66.6
13.3
N.A.
P-Site Similarity:
100
N.A.
46.6
100
N.A.
93.3
6.6
N.A.
100
N.A.
N.A.
6.6
N.A.
80
80
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
30
10
0
0
0
0
10
10
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
10
0
10
0
0
10
0
10
% D
% Glu:
10
0
0
0
30
0
10
0
70
0
10
0
0
10
0
% E
% Phe:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
60
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
10
70
50
0
% I
% Lys:
0
20
0
10
10
10
20
0
0
40
0
0
0
0
60
% K
% Leu:
0
10
0
60
0
0
10
0
20
10
0
70
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
60
0
0
0
0
0
0
0
0
20
10
0
0
0
0
% N
% Pro:
0
0
10
0
10
10
0
0
0
0
10
10
0
0
0
% P
% Gln:
10
0
0
0
20
0
0
0
0
10
0
0
0
10
0
% Q
% Arg:
0
0
70
0
0
0
0
0
0
10
0
10
0
0
0
% R
% Ser:
10
10
0
0
0
60
0
0
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
10
10
10
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
10
% V
% Trp:
0
0
10
0
0
10
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
60
0
10
0
0
0
60
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _