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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRPM3
All Species:
12.73
Human Site:
S276
Identified Species:
31.11
UniProt:
Q9HCF6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCF6
NP_001007472
1732
197543
S276
V
R
P
Y
Q
T
M
S
N
P
M
S
K
L
T
Chimpanzee
Pan troglodytes
XP_001140619
1707
194723
V257
G
I
A
P
W
G
I
V
E
N
Q
E
D
L
I
Rhesus Macaque
Macaca mulatta
XP_001091211
1815
206998
S359
V
R
P
Y
Q
T
M
S
N
P
M
S
K
L
T
Dog
Lupus familis
XP_849531
1579
180238
A245
G
R
A
S
D
I
L
A
F
G
H
K
Y
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q923J1
1863
212380
S307
V
L
E
Y
L
Q
E
S
P
P
V
P
V
V
V
Rat
Rattus norvegicus
Q925B3
1862
212335
S307
V
L
E
Y
L
Q
E
S
P
P
V
P
V
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424831
1660
189402
E280
P
V
V
A
L
I
V
E
G
G
P
N
V
I
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694167
1694
191528
S246
V
R
P
Y
Q
T
M
S
N
P
L
S
K
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A8DYE2
2023
225520
N306
N
H
E
L
L
G
H
N
R
E
V
P
C
H
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93971
2032
229044
L495
I
G
I
A
P
W
G
L
L
K
K
R
E
D
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
92.6
89.4
N.A.
45.4
45.2
N.A.
N.A.
87
N.A.
78.1
N.A.
36.6
N.A.
22.2
N.A.
Protein Similarity:
100
98.5
93.8
90.3
N.A.
62.4
62.5
N.A.
N.A.
91.2
N.A.
85.7
N.A.
53.7
N.A.
39.2
N.A.
P-Site Identity:
100
6.6
100
6.6
N.A.
26.6
26.6
N.A.
N.A.
0
N.A.
93.3
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
13.3
100
20
N.A.
40
40
N.A.
N.A.
26.6
N.A.
100
N.A.
20
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
20
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
10
10
0
% D
% Glu:
0
0
30
0
0
0
20
10
10
10
0
10
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% F
% Gly:
20
10
0
0
0
20
10
0
10
20
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
10
0
0
0
10
0
0
10
0
% H
% Ile:
10
10
10
0
0
20
10
0
0
0
0
0
0
10
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
10
10
30
0
0
% K
% Leu:
0
20
0
10
40
0
10
10
10
0
10
0
0
40
0
% L
% Met:
0
0
0
0
0
0
30
0
0
0
20
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
10
30
10
0
10
0
0
0
% N
% Pro:
10
0
30
10
10
0
0
0
20
50
10
30
0
0
0
% P
% Gln:
0
0
0
0
30
20
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
40
0
0
0
0
0
0
10
0
0
10
0
0
0
% R
% Ser:
0
0
0
10
0
0
0
50
0
0
0
30
0
10
20
% S
% Thr:
0
0
0
0
0
30
0
0
0
0
0
0
0
0
30
% T
% Val:
50
10
10
0
0
0
10
10
0
0
30
0
30
20
20
% V
% Trp:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
50
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _