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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CWC22
All Species:
29.7
Human Site:
S413
Identified Species:
50.26
UniProt:
Q9HCG8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCG8
NP_065994.1
908
105535
S413
L
D
E
G
D
T
D
S
N
T
D
Q
D
A
G
Chimpanzee
Pan troglodytes
XP_001157639
909
105673
S414
L
D
E
G
D
T
D
S
N
T
D
Q
D
A
G
Rhesus Macaque
Macaca mulatta
XP_001100012
907
105697
S413
L
D
E
G
D
T
D
S
N
T
D
Q
D
A
G
Dog
Lupus familis
XP_545549
908
105482
S413
L
D
E
G
D
S
D
S
N
T
D
Q
D
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5N3
908
104755
S411
L
D
E
G
D
S
D
S
N
T
D
Q
G
A
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515527
921
106628
S421
L
D
E
G
D
T
D
S
D
T
D
Q
D
A
K
Chicken
Gallus gallus
Q5ZKA3
926
108657
S419
L
D
E
G
D
S
E
S
E
P
D
Q
E
A
G
Frog
Xenopus laevis
Q52KN9
803
92701
F343
S
V
E
V
A
I
G
F
L
K
E
S
G
L
K
Zebra Danio
Brachydanio rerio
Q08C72
985
113331
S507
L
D
E
G
S
S
D
S
G
D
D
A
G
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJ87
1330
151618
S670
L
G
S
D
D
G
S
S
S
G
S
G
S
G
S
Honey Bee
Apis mellifera
XP_001120152
706
80124
L246
F
E
M
L
R
N
I
L
H
E
G
Q
L
D
K
Nematode Worm
Caenorhab. elegans
Q17336
897
104250
P425
L
N
V
F
K
L
D
P
E
F
E
K
N
E
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53333
577
67276
I117
D
Y
V
S
C
G
N
I
L
Q
C
L
S
I
L
Red Bread Mold
Neurospora crassa
Q7RX84
1010
113982
D472
L
G
E
A
S
D
D
D
E
D
D
D
D
D
D
Conservation
Percent
Protein Identity:
100
99.2
97.2
93.2
N.A.
84.2
N.A.
N.A.
77.5
70.6
67.1
60.9
N.A.
39.8
45.5
45.9
N.A.
Protein Similarity:
100
99.4
98.4
95.6
N.A.
90
N.A.
N.A.
86.5
80.2
74.6
71.8
N.A.
52.1
58.9
65.7
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
N.A.
N.A.
86.6
66.6
6.6
46.6
N.A.
20
6.6
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
93.3
86.6
13.3
53.3
N.A.
26.6
20
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.2
38.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.9
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
0
0
0
0
8
0
50
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
58
0
8
58
8
65
8
8
15
65
8
43
15
8
% D
% Glu:
0
8
72
0
0
0
8
0
22
8
15
0
8
8
8
% E
% Phe:
8
0
0
8
0
0
0
8
0
8
0
0
0
0
0
% F
% Gly:
0
15
0
58
0
15
8
0
8
8
8
8
22
15
43
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
8
8
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
8
0
8
0
0
22
% K
% Leu:
79
0
0
8
0
8
0
8
15
0
0
8
8
8
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
8
0
36
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
58
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
8
8
15
29
8
65
8
0
8
8
15
0
15
% S
% Thr:
0
0
0
0
0
29
0
0
0
43
0
0
0
0
0
% T
% Val:
0
8
15
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _