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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CWC22
All Species:
30.91
Human Site:
S698
Identified Species:
52.31
UniProt:
Q9HCG8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCG8
NP_065994.1
908
105535
S698
D
S
S
S
E
S
S
S
E
E
S
D
S
S
S
Chimpanzee
Pan troglodytes
XP_001157639
909
105673
S699
D
S
S
S
E
S
S
S
E
E
S
D
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001100012
907
105697
S698
D
S
S
S
E
S
S
S
E
E
S
D
S
S
S
Dog
Lupus familis
XP_545549
908
105482
S698
D
S
S
S
E
S
S
S
E
E
S
D
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5N3
908
104755
S703
S
D
A
S
D
S
S
S
S
S
S
T
Q
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515527
921
106628
S712
S
S
D
S
D
S
S
S
T
S
G
R
T
Q
E
Chicken
Gallus gallus
Q5ZKA3
926
108657
S701
S
S
S
D
S
S
S
S
S
S
D
S
S
D
S
Frog
Xenopus laevis
Q52KN9
803
92701
L612
D
S
L
P
W
S
V
L
E
C
M
N
L
S
E
Zebra Danio
Brachydanio rerio
Q08C72
985
113331
S791
E
S
D
S
D
S
S
S
D
S
D
S
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJ87
1330
151618
S963
D
S
S
E
E
D
S
S
S
D
S
S
S
E
S
Honey Bee
Apis mellifera
XP_001120152
706
80124
G515
Q
E
L
S
E
Y
M
G
L
S
K
L
N
Q
R
Nematode Worm
Caenorhab. elegans
Q17336
897
104250
S702
E
S
S
S
D
S
S
S
S
S
D
S
S
D
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53333
577
67276
K386
D
Q
L
R
I
L
G
K
F
W
G
H
L
I
S
Red Bread Mold
Neurospora crassa
Q7RX84
1010
113982
T752
R
G
R
S
L
S
R
T
P
P
R
R
G
R
G
Conservation
Percent
Protein Identity:
100
99.2
97.2
93.2
N.A.
84.2
N.A.
N.A.
77.5
70.6
67.1
60.9
N.A.
39.8
45.5
45.9
N.A.
Protein Similarity:
100
99.4
98.4
95.6
N.A.
90
N.A.
N.A.
86.5
80.2
74.6
71.8
N.A.
52.1
58.9
65.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
46.6
N.A.
N.A.
33.3
46.6
33.3
53.3
N.A.
60
13.3
53.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
60
N.A.
N.A.
46.6
46.6
40
73.3
N.A.
66.6
20
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.2
38.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.9
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
50
8
15
8
29
8
0
0
8
8
22
29
0
15
0
% D
% Glu:
15
8
0
8
43
0
0
0
36
29
0
0
0
8
15
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
8
8
0
0
15
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% K
% Leu:
0
0
22
0
8
8
0
8
8
0
0
8
15
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
8
8
0
0
0
0
0
% P
% Gln:
8
8
0
0
0
0
0
0
0
0
0
0
8
15
0
% Q
% Arg:
8
0
8
8
0
0
8
0
0
0
8
15
0
8
8
% R
% Ser:
22
72
50
72
8
79
72
72
29
43
43
29
58
50
72
% S
% Thr:
0
0
0
0
0
0
0
8
8
0
0
8
8
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _